Non-equilibrium cobalt(iii) "click" capsules

P. R. Symmers, M. J. Burke, D. P. August, P. I T Thomson, G. S. Nichol, M. R. Warren, C. J. Campbell, P. J. Lusby

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Cobalt(III) tetrahedral capsules have been prepared using an assembly-followed-by-oxidation protocol from a cobalt(II) precursor and a readily derivatizable pyridyl-triazole ligand system. Experiments designed to probe the constitutional dynamics show that these architectures are in a non-equilibrium state. A preliminary investigation into the host–guest chemistry of a water-soluble derivative shows it can bind and differentiate a range of different neutral organic molecules. The stability of this ensemble also permits the study of guest-binding at high salt concentrations.

LanguageEnglish
Pages756-760
Number of pages5
JournalChemical Science
Volume6
Issue number1
DOIs
Publication statusPublished - 7 Oct 2014
Externally publishedYes

Fingerprint

Cobalt
Capsules
Triazoles
Salts
Ligands
Derivatives
Oxidation
Molecules
Water
Experiments

Keywords

  • cobalt(iii)
  • molecular container species
  • drug delivery

Cite this

Symmers, P. R., Burke, M. J., August, D. P., Thomson, P. I. T., Nichol, G. S., Warren, M. R., ... Lusby, P. J. (2014). Non-equilibrium cobalt(iii) "click" capsules. Chemical Science, 6(1), 756-760. https://doi.org/10.1039/c4sc03036b
Symmers, P. R. ; Burke, M. J. ; August, D. P. ; Thomson, P. I T ; Nichol, G. S. ; Warren, M. R. ; Campbell, C. J. ; Lusby, P. J. / Non-equilibrium cobalt(iii) "click" capsules. In: Chemical Science. 2014 ; Vol. 6, No. 1. pp. 756-760.
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Symmers, PR, Burke, MJ, August, DP, Thomson, PIT, Nichol, GS, Warren, MR, Campbell, CJ & Lusby, PJ 2014, 'Non-equilibrium cobalt(iii) "click" capsules' Chemical Science, vol. 6, no. 1, pp. 756-760. https://doi.org/10.1039/c4sc03036b

Non-equilibrium cobalt(iii) "click" capsules. / Symmers, P. R.; Burke, M. J.; August, D. P.; Thomson, P. I T; Nichol, G. S.; Warren, M. R.; Campbell, C. J.; Lusby, P. J.

In: Chemical Science, Vol. 6, No. 1, 07.10.2014, p. 756-760.

Research output: Contribution to journalArticle

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Symmers PR, Burke MJ, August DP, Thomson PIT, Nichol GS, Warren MR et al. Non-equilibrium cobalt(iii) "click" capsules. Chemical Science. 2014 Oct 7;6(1):756-760. https://doi.org/10.1039/c4sc03036b