Non-equilibrium cobalt(iii) "click" capsules

P. R. Symmers, M. J. Burke, D. P. August, P. I T Thomson, G. S. Nichol, M. R. Warren, C. J. Campbell, P. J. Lusby

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36 Citations (Scopus)
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Abstract

Cobalt(III) tetrahedral capsules have been prepared using an assembly-followed-by-oxidation protocol from a cobalt(II) precursor and a readily derivatizable pyridyl-triazole ligand system. Experiments designed to probe the constitutional dynamics show that these architectures are in a non-equilibrium state. A preliminary investigation into the host–guest chemistry of a water-soluble derivative shows it can bind and differentiate a range of different neutral organic molecules. The stability of this ensemble also permits the study of guest-binding at high salt concentrations.

Original languageEnglish
Pages (from-to)756-760
Number of pages5
JournalChemical Science
Volume6
Issue number1
DOIs
Publication statusPublished - 7 Oct 2014
Externally publishedYes

Keywords

  • cobalt(iii)
  • molecular container species
  • drug delivery

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  • Cite this

    Symmers, P. R., Burke, M. J., August, D. P., Thomson, P. I. T., Nichol, G. S., Warren, M. R., Campbell, C. J., & Lusby, P. J. (2014). Non-equilibrium cobalt(iii) "click" capsules. Chemical Science, 6(1), 756-760. https://doi.org/10.1039/c4sc03036b