Nickel-promoted recognition of long DNA sites by designed peptide derivatives

Jéssica Rodríguez; Jesús Mosquera; M. Eugenio Vázquez; José L. Mascareñas

doi:10.1002/chem.201602783

Nickel-promoted recognition of long DNA sites by designed peptide derivatives

Jéssica Rodríguez, Jesús Mosquera, M. Eugenio Vázquez, José L. Mascareñas

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

We describe the synthesis of designed peptidic modules that self-assemble in specific DNA sequences of 12 base pairs in the presence of Ni^IIsalts. The modules consist of modified fragments of transcription factors that have been appropriately engineered to include metal-chelating His and bipyridine ligands.

Original language	English
Pages (from-to)	13474-13477
Number of pages	4
Journal	Chemistry - A European Journal
Volume	22
Issue number	38
Early online date	3 Aug 2016
DOIs	https://doi.org/10.1002/chem.201602783
Publication status	Published - 6 Sept 2016

Keywords

DNA recognition
metallosupramolecular chemistry
minor groove binder
peptides
self-assembly

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10.1002/chem.201602783

Cite this

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AU - Mosquera, Jesús

AU - Vázquez, M. Eugenio

AU - Mascareñas, José L.

PY - 2016/9/6

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KW - metallosupramolecular chemistry

KW - minor groove binder

KW - peptides

KW - self-assembly

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Nickel-promoted recognition of long DNA sites by designed peptide derivatives

Abstract

Keywords

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