New roles for endosomes: from vesicular carriers to multi-purpose platforms

Gwyn W. Gould, Jennifer Lippincott-Schwartz

Research output: Contribution to journalReview articlepeer-review

165 Citations (Scopus)


The careful sorting and recycling of membranes and cargo and the intracellular delivery of proteins, toxins and viruses by endocytosis are well-established roles for the endocytic apparatus, which is present in all eukaryotic cells. Recently, it has become clear that endosomes have key roles in such diverse processes as cytokinesis, polarization and migration, in which their functions might be distinct from those classically associated with endosomes. We speculate that endosomes function as multifunctional platforms on which unique sets of molecular machines are assembled to suit different cellular roles.

Original languageEnglish
Pages (from-to)287-292
Number of pages6
JournalNature Reviews Molecular Cell Biology
Issue number4
Publication statusPublished - 11 Mar 2009


  • endosomes
  • vesicular carriers


Dive into the research topics of 'New roles for endosomes: from vesicular carriers to multi-purpose platforms'. Together they form a unique fingerprint.

Cite this