New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp

Suwigarn Pedpradab, RuAngelie Edrada, Rainer Ebel, Victor Wray, Peter Proksch, Ruangelie Edrada-Ebel

Research output: Contribution to journalArticle

35 Citations (Scopus)


Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.

Original languageEnglish
Pages (from-to)2113-2116
Number of pages4
JournalJournal of Natural Products
Issue number12
Publication statusPublished - Dec 2004


  • alkaloids
  • carbolines
  • nuclear magnetic resonance
  • oceans and seas
  • porifera


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