New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp

Suwigarn Pedpradab; RuAngelie Edrada; Rainer Ebel; Victor Wray; Peter Proksch; Ruangelie Edrada-Ebel

doi:10.1021/np0401516

New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp

Suwigarn Pedpradab, RuAngelie Edrada, Rainer Ebel, Victor Wray, Peter Proksch, Ruangelie Edrada-Ebel

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article

36 Citations (Scopus)

Abstract

Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.

Original language	English
Pages (from-to)	2113-2116
Number of pages	4
Journal	Journal of Natural Products
Volume	67
Issue number	12
DOIs	https://doi.org/10.1021/np0401516
Publication status	Published - Dec 2004

Keywords

alkaloids
carbolines
nuclear magnetic resonance
oceans and seas
porifera

Access to Document

10.1021/np0401516

Cite this

@article{f7534731d971498389204be0d6b9cf0a,

title = "New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp",

abstract = "Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.",

keywords = "alkaloids, carbolines, nuclear magnetic resonance, oceans and seas, porifera",

author = "Suwigarn Pedpradab and RuAngelie Edrada and Rainer Ebel and Victor Wray and Peter Proksch and Ruangelie Edrada-Ebel",

year = "2004",

month = dec,

doi = "10.1021/np0401516",

language = "English",

volume = "67",

pages = "2113--2116",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "12",

}

TY - JOUR

T1 - New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp

AU - Pedpradab, Suwigarn

AU - Edrada, RuAngelie

AU - Ebel, Rainer

AU - Wray, Victor

AU - Proksch, Peter

AU - Edrada-Ebel, Ruangelie

PY - 2004/12

Y1 - 2004/12

N2 - Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.

AB - Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.

KW - alkaloids

KW - carbolines

KW - nuclear magnetic resonance

KW - oceans and seas

KW - porifera

U2 - 10.1021/np0401516

DO - 10.1021/np0401516

M3 - Article

C2 - 15620266

SN - 0163-3864

VL - 67

SP - 2113

EP - 2116

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 12

ER -

New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp

Abstract

Keywords

Access to Document

Fingerprint

Cite this