Abstract
In this review the benefits of using a drug delivery system (DDS) to improve therapeutic outcome will be discussed using treatment of visceral leishmaniasis with amphotericin B (AMB), a poorly water soluble drug, as an exemplar. Progress in producing AMB formulations that can be given by intravenous, oral and pulmonary routes of administration is discussed.
| Original language | English |
|---|---|
| Title of host publication | Drug Discovery in Leishmaniasis |
| Editors | Luis Rivas, Carmen Gil |
| Place of Publication | Croydon |
| Publisher | Royal Society of Chemistry |
| Chapter | 11 |
| Pages | 224 - 234 |
| Number of pages | 11 |
| ISBN (Electronic) | 9781788012584 |
| ISBN (Print) | 9781782628897 |
| Publication status | Published - 1 Nov 2017 |
Keywords
- Leishmania
- drug discovery
- drug delivery system
- therapeutic outcomes
- visceral leishmaniasis
- intravenous administration
- oral administration
- pulmonary administration