New avenues for drug delivery in Leishmania: using treatment of visceral leishmaniasis with amphotericin B as an exemplar.

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this review the benefits of using a drug delivery system (DDS) to improve therapeutic outcome will be discussed using treatment of visceral leishmaniasis with amphotericin B (AMB), a poorly water soluble drug, as an exemplar. Progress in producing AMB formulations that can be given by intravenous, oral and pulmonary routes of administration is discussed.
Original languageEnglish
Title of host publicationDrug Discovery in Leishmaniasis
PublisherRoyal Society of Chemistry
Number of pages15
Publication statusAccepted/In press - 20 Dec 2016

Keywords

  • Leishmania
  • drug discovery
  • drug delivery system
  • therapeutic outcomes
  • visceral leishmaniasis
  • intravenous administration
  • oral administration
  • pulmonary administration

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