Natural products for high-throughput screening

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Not all traditional remedies are likely to be proven to be efficacious in scientific studies. This means that natural product researchers are going to accumulate negative results along with considerable information about the chemistry and biology of components found in the ingredients of the traditional leads. In any sizeable or long-term research programe involving natural product leads, there will be a large collection of background information and, potentially, a large number of apparently inactive extracts and compounds. Can something of value be done with such material? Since the vast majority of pharmaceutical drug discovery does not involve ethnopharmacological leads but is centered on high-throughput screening of the widest possible chemical diversity, the answer to this question has to be 'yes'. The difficulty in realizing the value of natural products for industrial drug discovery is in the area of communications between industrial and natural product researchers. There needs to be education in both directions: about issues relating to the Convention on Biological Diversity to industry, and about the technological demands of high-throughput screening to natural product researchers.

LanguageEnglish
Title of host publicationEthnomedicine and Drug Discovery
EditorsM.M. Iwu, J. Wootton
Place of PublicationAmsterdam
Chapter2
Pages39-44
Number of pages6
DOIs
Publication statusPublished - 1 Mar 2002

Publication series

NameAdvances in Phytomedicine
Volume1
ISSN (Print)1572-557X

Fingerprint

Biological Products
researchers
screening
drugs
Research Personnel
Drug Discovery
communication (human)
education
chemistry
ingredients
biodiversity
Biodiversity
industry
Biological Sciences
extracts
Industry
Education
Research
Pharmaceutical Preparations

Keywords

  • combinatorial chemistry
  • drug discovery
  • high-throughput screening
  • natural products
  • pharmaceutical industry
  • UN Convention on Biological Diversity

Cite this

Harvey, A. L. (2002). Natural products for high-throughput screening. In M. M. Iwu, & J. Wootton (Eds.), Ethnomedicine and Drug Discovery (pp. 39-44). (Advances in Phytomedicine; Vol. 1). Amsterdam. https://doi.org/10.1016/S1572-557X(02)80011-3
Harvey, Alan L. / Natural products for high-throughput screening. Ethnomedicine and Drug Discovery. editor / M.M. Iwu ; J. Wootton. Amsterdam, 2002. pp. 39-44 (Advances in Phytomedicine).
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Harvey, AL 2002, Natural products for high-throughput screening. in MM Iwu & J Wootton (eds), Ethnomedicine and Drug Discovery. Advances in Phytomedicine, vol. 1, Amsterdam, pp. 39-44. https://doi.org/10.1016/S1572-557X(02)80011-3

Natural products for high-throughput screening. / Harvey, Alan L.

Ethnomedicine and Drug Discovery. ed. / M.M. Iwu; J. Wootton. Amsterdam, 2002. p. 39-44 (Advances in Phytomedicine; Vol. 1).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Harvey AL. Natural products for high-throughput screening. In Iwu MM, Wootton J, editors, Ethnomedicine and Drug Discovery. Amsterdam. 2002. p. 39-44. (Advances in Phytomedicine). https://doi.org/10.1016/S1572-557X(02)80011-3