Nanostructured hydrogels for three-dimensional cell culture through self-assembly of fluorenylmethoxycarbonyl-dipeptides

V  Jayawarna; M  Ali; T A  Jowitt; A E  Miller; A  Saiani; J E  Gough; R V  Ulijn

doi:10.1002/adma.200501522

Nanostructured hydrogels for three-dimensional cell culture through self-assembly of fluorenylmethoxycarbonyl-dipeptides

V Jayawarna, M Ali, T A Jowitt, A E Miller, A Saiani, J E Gough, R V Ulijn

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945 Citations (Scopus)

Abstract

A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.

Original language	English
Pages (from-to)	611-614
Number of pages	5
Journal	Advanced Materials
Volume	18
Issue number	5
DOIs	https://doi.org/10.1002/adma.200501522
Publication status	Published - 3 Mar 2006

Keywords

nanostructured hydrogels
three-dimensional cell culture
fluorenylmethoxycarbonyl-dipeptides
self-assembly

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10.1002/adma.200501522

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title = "Nanostructured hydrogels for three-dimensional cell culture through self-assembly of fluorenylmethoxycarbonyl-dipeptides",

abstract = "A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.",

keywords = "nanostructured hydrogels, three-dimensional cell culture, fluorenylmethoxycarbonyl-dipeptides, self-assembly",

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AU - Jayawarna, V

AU - Ali, M

AU - Jowitt, T A

AU - Miller, A E

AU - Saiani, A

AU - Gough, J E

AU - Ulijn, R V

PY - 2006/3/3

Y1 - 2006/3/3

N2 - A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.

AB - A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.

KW - nanostructured hydrogels

KW - three-dimensional cell culture

KW - fluorenylmethoxycarbonyl-dipeptides

KW - self-assembly

U2 - 10.1002/adma.200501522

DO - 10.1002/adma.200501522

M3 - Article

SN - 0935-9648

VL - 18

SP - 611

EP - 614

JO - Advanced Materials

JF - Advanced Materials

IS - 5

ER -

Nanostructured hydrogels for three-dimensional cell culture through self-assembly of fluorenylmethoxycarbonyl-dipeptides

Abstract

Keywords

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