Nanophase separated amphiphilic microbeads

Gabriela Savin, Nico Bruns, Yi Thomann, Joerg C. Tiller

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The synthesis of nonporous nanophase separated amphiphilic microbeads was investigated. The synthesis was performed with a mixture of α,ω- methacrylate-terminated poly-dimethylsiloxane (MA-PDMS-MA), trimethylsilylated 2-hydroxyethylacrylate (TMSOEA) and the photoinitiator Irgacure 651 emulsified in a surfactant solution in 100 mM phosphate buffer, pH 7.0. Attenuated total reflection (ATR) and fourier transform infrared (FTIR) was used to investigate the chemical composition of the particles near their surface. The amphiphilic microbeads showed the phase separation in bulk as well as on the surface and was found to be effective as solid-phase transfer of a α-chymotrypsin- catalyzed biotransformation in octane.

LanguageEnglish
Pages7536-7539
Number of pages4
JournalMacromolecules
Volume38
Issue number18
DOIs
Publication statusPublished - 6 Sep 2005

Fingerprint

Methacrylates
Polydimethylsiloxane
Surface-Active Agents
Phase separation
Fourier transforms
Buffers
Phosphates
Surface active agents
Infrared radiation
Chemical analysis
octane
baysilon
6-hydroxy-7-methoxyphthalide
Biotransformation
alpha-chymotrypsin

Keywords

  • amphiphilic microbeads

Cite this

Savin, G., Bruns, N., Thomann, Y., & Tiller, J. C. (2005). Nanophase separated amphiphilic microbeads. Macromolecules, 38(18), 7536-7539. https://doi.org/10.1021/ma0509715
Savin, Gabriela ; Bruns, Nico ; Thomann, Yi ; Tiller, Joerg C. / Nanophase separated amphiphilic microbeads. In: Macromolecules. 2005 ; Vol. 38, No. 18. pp. 7536-7539.
@article{aa11a543397247ae95cb6e21207cd746,
title = "Nanophase separated amphiphilic microbeads",
abstract = "The synthesis of nonporous nanophase separated amphiphilic microbeads was investigated. The synthesis was performed with a mixture of α,ω- methacrylate-terminated poly-dimethylsiloxane (MA-PDMS-MA), trimethylsilylated 2-hydroxyethylacrylate (TMSOEA) and the photoinitiator Irgacure 651 emulsified in a surfactant solution in 100 mM phosphate buffer, pH 7.0. Attenuated total reflection (ATR) and fourier transform infrared (FTIR) was used to investigate the chemical composition of the particles near their surface. The amphiphilic microbeads showed the phase separation in bulk as well as on the surface and was found to be effective as solid-phase transfer of a α-chymotrypsin- catalyzed biotransformation in octane.",
keywords = "amphiphilic microbeads",
author = "Gabriela Savin and Nico Bruns and Yi Thomann and Tiller, {Joerg C.}",
year = "2005",
month = "9",
day = "6",
doi = "10.1021/ma0509715",
language = "English",
volume = "38",
pages = "7536--7539",
journal = "Macromolecules",
issn = "0024-9297",
publisher = "American Chemical Society",
number = "18",

}

Savin, G, Bruns, N, Thomann, Y & Tiller, JC 2005, 'Nanophase separated amphiphilic microbeads' Macromolecules, vol. 38, no. 18, pp. 7536-7539. https://doi.org/10.1021/ma0509715

Nanophase separated amphiphilic microbeads. / Savin, Gabriela; Bruns, Nico; Thomann, Yi; Tiller, Joerg C.

In: Macromolecules, Vol. 38, No. 18, 06.09.2005, p. 7536-7539.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Nanophase separated amphiphilic microbeads

AU - Savin, Gabriela

AU - Bruns, Nico

AU - Thomann, Yi

AU - Tiller, Joerg C.

PY - 2005/9/6

Y1 - 2005/9/6

N2 - The synthesis of nonporous nanophase separated amphiphilic microbeads was investigated. The synthesis was performed with a mixture of α,ω- methacrylate-terminated poly-dimethylsiloxane (MA-PDMS-MA), trimethylsilylated 2-hydroxyethylacrylate (TMSOEA) and the photoinitiator Irgacure 651 emulsified in a surfactant solution in 100 mM phosphate buffer, pH 7.0. Attenuated total reflection (ATR) and fourier transform infrared (FTIR) was used to investigate the chemical composition of the particles near their surface. The amphiphilic microbeads showed the phase separation in bulk as well as on the surface and was found to be effective as solid-phase transfer of a α-chymotrypsin- catalyzed biotransformation in octane.

AB - The synthesis of nonporous nanophase separated amphiphilic microbeads was investigated. The synthesis was performed with a mixture of α,ω- methacrylate-terminated poly-dimethylsiloxane (MA-PDMS-MA), trimethylsilylated 2-hydroxyethylacrylate (TMSOEA) and the photoinitiator Irgacure 651 emulsified in a surfactant solution in 100 mM phosphate buffer, pH 7.0. Attenuated total reflection (ATR) and fourier transform infrared (FTIR) was used to investigate the chemical composition of the particles near their surface. The amphiphilic microbeads showed the phase separation in bulk as well as on the surface and was found to be effective as solid-phase transfer of a α-chymotrypsin- catalyzed biotransformation in octane.

KW - amphiphilic microbeads

UR - http://www.scopus.com/inward/record.url?scp=25144448153&partnerID=8YFLogxK

U2 - 10.1021/ma0509715

DO - 10.1021/ma0509715

M3 - Article

VL - 38

SP - 7536

EP - 7539

JO - Macromolecules

T2 - Macromolecules

JF - Macromolecules

SN - 0024-9297

IS - 18

ER -