Nanoparticle-enhanced diffraction gratings for ultrasensitive surface plasmon biosensing

A.W. Wark; Hye Jin Lee; A.J. Qavi; R.M. Corn

doi:10.1021/ac071062b

Nanoparticle-enhanced diffraction gratings for ultrasensitive surface plasmon biosensing

A.W. Wark, Hye Jin Lee, A.J. Qavi, R.M. Corn

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

Ultrasensitive surface bioaffinity sensors are created by the adsorption of gold nanoparticles onto gold diffraction gratings. An enhanced diffraction obtained in a surface plasmon resonance geometry is observed due to the optical coupling of the planar surface plasmons in the grating to the localized surface plasmons in the gold nanoparticles. As a first example, these nanoparticle grating biosensors are employed to detect unmodified DNA at a concentration of 10 fM.

Original language	English
Pages (from-to)	6697-6701
Number of pages	5
Journal	Analytical Chemistry
Volume	79
Issue number	17
DOIs	https://doi.org/10.1021/ac071062b
Publication status	Published - 3 Aug 2007

Keywords

bioaffinity sensors
adsorption
gold nanoparticles
diffraction gratings
plasmons
unmodified DNA

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10.1021/ac071062b

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title = "Nanoparticle-enhanced diffraction gratings for ultrasensitive surface plasmon biosensing",

abstract = "Ultrasensitive surface bioaffinity sensors are created by the adsorption of gold nanoparticles onto gold diffraction gratings. An enhanced diffraction obtained in a surface plasmon resonance geometry is observed due to the optical coupling of the planar surface plasmons in the grating to the localized surface plasmons in the gold nanoparticles. As a first example, these nanoparticle grating biosensors are employed to detect unmodified DNA at a concentration of 10 fM. ",

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AU - Qavi, A.J.

AU - Corn, R.M.

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N2 - Ultrasensitive surface bioaffinity sensors are created by the adsorption of gold nanoparticles onto gold diffraction gratings. An enhanced diffraction obtained in a surface plasmon resonance geometry is observed due to the optical coupling of the planar surface plasmons in the grating to the localized surface plasmons in the gold nanoparticles. As a first example, these nanoparticle grating biosensors are employed to detect unmodified DNA at a concentration of 10 fM.

AB - Ultrasensitive surface bioaffinity sensors are created by the adsorption of gold nanoparticles onto gold diffraction gratings. An enhanced diffraction obtained in a surface plasmon resonance geometry is observed due to the optical coupling of the planar surface plasmons in the grating to the localized surface plasmons in the gold nanoparticles. As a first example, these nanoparticle grating biosensors are employed to detect unmodified DNA at a concentration of 10 fM.

KW - bioaffinity sensors

KW - adsorption

KW - gold nanoparticles

KW - diffraction gratings

KW - plasmons

KW - unmodified DNA

U2 - 10.1021/ac071062b

DO - 10.1021/ac071062b

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JF - Analytical Chemistry

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