Multipoint viscosity measurements in microfluidic channels using optical tweezers

Stephen Keen, Alison Yao, Jonathan Leach, Roberto Di Leonardo, Chris Saunter, Gordon Love, Jonathan Cooper, Miles Padgett

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

We demonstrate the technique of multipoint viscosity measurements incorporating the accurate calibration of micron sized particles. We describe the use of a high-speed camera to measure the residual motion of particles trapped in holographic optical tweezers, enabling us to calculate the fluid viscosity at multiple points across the field-of-view of the microscope within a microfluidic system.

Original languageEnglish
Pages (from-to)2059-2062
Number of pages4
JournalLab on a Chip
Volume9
Issue number14
DOIs
Publication statusPublished - 2009

Keywords

  • force microscopy
  • local viscosity
  • living cells
  • microrheology
  • position
  • calibration
  • detector
  • systems
  • flow

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    Keen, S., Yao, A., Leach, J., Di Leonardo, R., Saunter, C., Love, G., Cooper, J., & Padgett, M. (2009). Multipoint viscosity measurements in microfluidic channels using optical tweezers. Lab on a Chip, 9(14), 2059-2062. https://doi.org/10.1039/b900934e