Abstract
The dinuclear platinum complex trans-[{Pt(NH3)2Cl}2μ-dpzm]2+ (di-Pt) binds inside cucurbit[7]uril with slow exchange kinetics which does not significantly affect the cytotoxicity of the dinuclear complex but reactivity at the platinum centre is reduced.
| Original language | English |
|---|---|
| Pages (from-to) | 1424-1425 |
| Number of pages | 2 |
| Journal | Chemical Communications (London) |
| Volume | 12 |
| DOIs | |
| Publication status | Published - 2004 |
Keywords
- toxicity
- cancer treatment
- platinum complexes
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Cite this
Wheate, N. J., Day, A. I., Blanch, R. J., Arnold, A. P., Cullinane, C., & Collins, J. G. (2004). Multi-nuclear platinum complexes encapsulated in cucurbit[n]uril as an approach to reduce toxicity in cancer treatment. Chemical Communications (London), 12, 1424-1425. https://doi.org/10.1039/b404358h