The hydrotris(methimazolyl)borate anion (TmMe) has been used to synthesize an alternative functional model ([Mo(TmMe)(O)2Cl]) of the metalloenzyme sulfite oxidase. It has been shown that the complex undergoes oxygen atom transfer chemistry and that it performs the primary function of the enzyme, sulfite oxidation. A method using ion chromatography has been developed to definitively prove that sulfite is oxidized to sulfate.
- sulfite oxidase
- inorganic chemistry
Spicer, M., Reglinski, J., Wallace, D., & Gibson, L. (2007). [Mo(TmMe)(O)2Cl]: an alternative functional model of sulfite oxidase. Inorganic Chemistry, 46, 3804 - 3806. https://doi.org/10.1021/ic700468m