Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication

C. Torres-Sanchez, J. R. Corney

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The successful manufacture of functionally tailored materials (e.g., density engineered foams) for advanced applications (e.g., structures or in bioengineering) requires an effective control over the process variables. In order to achieve this, density gradation needs to be represented and quantified. Current density measurement techniques offer information on bulk values, but neglect local position as valuable information (i.e., do not associate density scalar values with specific location, which is frequently critical when mechanical properties or functionalities have to be engineered). In this article, we present a method that characterizes the density gradation of engineered foams manufactured by the sonication technique, which allows the generation of sophisticated porous architectures beyond a simple linear gradient. A 3D data capture (mu CT) and a flexible analysis software program (ImageJ) are used to obtain "global" density gradation values that can, ultimately, inform, control, and optimize the manufacture process. Polymeric foams, i.e., polyurethane (PU) foams, were used in this study as proof of concept. The measurements performed on the PU foams were validated by checking consistency in the results for both horizontal and vertical image slices. Biological characterization was done to assess the samples' tailored structure viability as scaffolds for tissue engineering. The comparison between untreated and sonicated samples yielded a 12.7% of increment in living cell count adhered to the walls after treatment. The conclusions drawn from this study may inform the design and manufacture of density-engineered materials used in other fields (e.g., structural materials, optoelectronics, food technology, etc.)

LanguageEnglish
Pages490-499
Number of pages10
JournalJournal of Materials Science
Volume46
Issue number2
DOIs
Publication statusPublished - Jan 2011

Fingerprint

Sonication
Foams
Ultrasonics
Food technology
Polyurethanes
Electric current measurement
Tissue engineering
Optoelectronic devices
Data acquisition
Current density
Cells
Scaffolds (biology)
Mechanical properties
polyurethane foam

Keywords

  • porous materials
  • scaffolds
  • ceramics
  • aluminium
  • porosity
  • design

Cite this

@article{a50eee0a71b04e68ad2446ac9377a65e,
title = "Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication",
abstract = "The successful manufacture of functionally tailored materials (e.g., density engineered foams) for advanced applications (e.g., structures or in bioengineering) requires an effective control over the process variables. In order to achieve this, density gradation needs to be represented and quantified. Current density measurement techniques offer information on bulk values, but neglect local position as valuable information (i.e., do not associate density scalar values with specific location, which is frequently critical when mechanical properties or functionalities have to be engineered). In this article, we present a method that characterizes the density gradation of engineered foams manufactured by the sonication technique, which allows the generation of sophisticated porous architectures beyond a simple linear gradient. A 3D data capture (mu CT) and a flexible analysis software program (ImageJ) are used to obtain {"}global{"} density gradation values that can, ultimately, inform, control, and optimize the manufacture process. Polymeric foams, i.e., polyurethane (PU) foams, were used in this study as proof of concept. The measurements performed on the PU foams were validated by checking consistency in the results for both horizontal and vertical image slices. Biological characterization was done to assess the samples' tailored structure viability as scaffolds for tissue engineering. The comparison between untreated and sonicated samples yielded a 12.7{\%} of increment in living cell count adhered to the walls after treatment. The conclusions drawn from this study may inform the design and manufacture of density-engineered materials used in other fields (e.g., structural materials, optoelectronics, food technology, etc.)",
keywords = "porous materials, scaffolds, ceramics, aluminium, porosity, design",
author = "C. Torres-Sanchez and Corney, {J. R.}",
year = "2011",
month = "1",
doi = "10.1007/s10853-010-4944-z",
language = "English",
volume = "46",
pages = "490--499",
journal = "Journal of Materials Science",
issn = "0022-2461",
number = "2",

}

Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication. / Torres-Sanchez, C.; Corney, J. R.

In: Journal of Materials Science, Vol. 46, No. 2, 01.2011, p. 490-499.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Morphological and biological characterization of density engineered foams fabricated by ultrasonic sonication

AU - Torres-Sanchez, C.

AU - Corney, J. R.

PY - 2011/1

Y1 - 2011/1

N2 - The successful manufacture of functionally tailored materials (e.g., density engineered foams) for advanced applications (e.g., structures or in bioengineering) requires an effective control over the process variables. In order to achieve this, density gradation needs to be represented and quantified. Current density measurement techniques offer information on bulk values, but neglect local position as valuable information (i.e., do not associate density scalar values with specific location, which is frequently critical when mechanical properties or functionalities have to be engineered). In this article, we present a method that characterizes the density gradation of engineered foams manufactured by the sonication technique, which allows the generation of sophisticated porous architectures beyond a simple linear gradient. A 3D data capture (mu CT) and a flexible analysis software program (ImageJ) are used to obtain "global" density gradation values that can, ultimately, inform, control, and optimize the manufacture process. Polymeric foams, i.e., polyurethane (PU) foams, were used in this study as proof of concept. The measurements performed on the PU foams were validated by checking consistency in the results for both horizontal and vertical image slices. Biological characterization was done to assess the samples' tailored structure viability as scaffolds for tissue engineering. The comparison between untreated and sonicated samples yielded a 12.7% of increment in living cell count adhered to the walls after treatment. The conclusions drawn from this study may inform the design and manufacture of density-engineered materials used in other fields (e.g., structural materials, optoelectronics, food technology, etc.)

AB - The successful manufacture of functionally tailored materials (e.g., density engineered foams) for advanced applications (e.g., structures or in bioengineering) requires an effective control over the process variables. In order to achieve this, density gradation needs to be represented and quantified. Current density measurement techniques offer information on bulk values, but neglect local position as valuable information (i.e., do not associate density scalar values with specific location, which is frequently critical when mechanical properties or functionalities have to be engineered). In this article, we present a method that characterizes the density gradation of engineered foams manufactured by the sonication technique, which allows the generation of sophisticated porous architectures beyond a simple linear gradient. A 3D data capture (mu CT) and a flexible analysis software program (ImageJ) are used to obtain "global" density gradation values that can, ultimately, inform, control, and optimize the manufacture process. Polymeric foams, i.e., polyurethane (PU) foams, were used in this study as proof of concept. The measurements performed on the PU foams were validated by checking consistency in the results for both horizontal and vertical image slices. Biological characterization was done to assess the samples' tailored structure viability as scaffolds for tissue engineering. The comparison between untreated and sonicated samples yielded a 12.7% of increment in living cell count adhered to the walls after treatment. The conclusions drawn from this study may inform the design and manufacture of density-engineered materials used in other fields (e.g., structural materials, optoelectronics, food technology, etc.)

KW - porous materials

KW - scaffolds

KW - ceramics

KW - aluminium

KW - porosity

KW - design

UR - http://www.scopus.com/inward/record.url?scp=78650731210&partnerID=8YFLogxK

U2 - 10.1007/s10853-010-4944-z

DO - 10.1007/s10853-010-4944-z

M3 - Article

VL - 46

SP - 490

EP - 499

JO - Journal of Materials Science

T2 - Journal of Materials Science

JF - Journal of Materials Science

SN - 0022-2461

IS - 2

ER -