Molar efficiency: a useful metric to gauge relative reaction efficiency in discovery medicinal chemistry

Fiona I. McGonagle, Helen F. Sneddon, Craig Jamieson, Allan Watson

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The concept of molar efficiency is introduced as a new metric to enable assessment of reaction efficiency in discovery medicinal chemistry. Calculations from molar units enable cross-comparison of the broad range of transformations employed in discovery-phase medicinal chemistry research and is proposed to facilitate identification of more sustainable synthetic transformations.

Original languageEnglish
Pages (from-to)523-532
Number of pages10
JournalACS Sustainable Chemistry and Engineering
Volume2
Issue number3
DOIs
Publication statusPublished - 3 Mar 2014

Keywords

  • discovery medicinal chemistry
  • reaction efficiency
  • metrics

Fingerprint Dive into the research topics of 'Molar efficiency: a useful metric to gauge relative reaction efficiency in discovery medicinal chemistry'. Together they form a unique fingerprint.

Cite this