Modulation of autoimmune and allergic responses by defined nematode molecules

W. Harnett; L. Al-Riyami; J. Rzepecka; M. M. Harnett

doi:10.1079/9781845937591.0144

Modulation of autoimmune and allergic responses by defined nematode molecules

W. Harnett, L. Al-Riyami, J. Rzepecka, M. M. Harnett

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter explores the immunomodulatory effects of nematode infections which protect the host against autoimmune and allergic diseases. Included are discussions on specific nematode molecules (i.e., Ascaris suum PAS-1, cystatins, Dirofilaria immitis-derived antigen (DiAg), galectin-9 homologue of Toxascaris leonina (Tl-GAL), ES-62) that exert immunomodulatory properties in animal studies and their probable mechanisms of action.

Original language	English
Title of host publication	Parasitic Nematodes
Subtitle of host publication	Molecular Biology, Biochemistry and Immunology
Editors	M. W. Kennedy, W. Harnett
Pages	144-155
Number of pages	12
DOIs	https://doi.org/10.1079/9781845937591.0144
Publication status	Published - 2013

Keywords

allergies
animal parasitic nematodes
autoimmune diseases
disease models
excretory–secretory products
experimental infections
helminthoses
helminths
human disease
immune response
immunomodulatory properties
infections
laboratory animals
nematode infections
parasites
parisitoses

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1079/9781845937591.0144

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title = "Modulation of autoimmune and allergic responses by defined nematode molecules",

abstract = "This chapter explores the immunomodulatory effects of nematode infections which protect the host against autoimmune and allergic diseases. Included are discussions on specific nematode molecules (i.e., Ascaris suum PAS-1, cystatins, Dirofilaria immitis-derived antigen (DiAg), galectin-9 homologue of Toxascaris leonina (Tl-GAL), ES-62) that exert immunomodulatory properties in animal studies and their probable mechanisms of action.",

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year = "2013",

doi = "10.1079/9781845937591.0144",

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pages = "144--155",

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AU - Harnett, W.

AU - Al-Riyami, L.

AU - Rzepecka, J.

AU - Harnett, M. M.

PY - 2013

Y1 - 2013

N2 - This chapter explores the immunomodulatory effects of nematode infections which protect the host against autoimmune and allergic diseases. Included are discussions on specific nematode molecules (i.e., Ascaris suum PAS-1, cystatins, Dirofilaria immitis-derived antigen (DiAg), galectin-9 homologue of Toxascaris leonina (Tl-GAL), ES-62) that exert immunomodulatory properties in animal studies and their probable mechanisms of action.

AB - This chapter explores the immunomodulatory effects of nematode infections which protect the host against autoimmune and allergic diseases. Included are discussions on specific nematode molecules (i.e., Ascaris suum PAS-1, cystatins, Dirofilaria immitis-derived antigen (DiAg), galectin-9 homologue of Toxascaris leonina (Tl-GAL), ES-62) that exert immunomodulatory properties in animal studies and their probable mechanisms of action.

KW - allergies

KW - animal parasitic nematodes

KW - autoimmune diseases

KW - disease models

KW - excretory–secretory products

KW - experimental infections

KW - helminthoses

KW - helminths

KW - human disease

KW - immune response

KW - immunomodulatory properties

KW - infections

KW - laboratory animals

KW - nematode infections

KW - parasites

KW - parisitoses

U2 - 10.1079/9781845937591.0144

DO - 10.1079/9781845937591.0144

M3 - Chapter

SN - 9781845937591

SP - 144

EP - 155

BT - Parasitic Nematodes

A2 - Kennedy, M. W.

A2 - Harnett, W.

ER -

Modulation of autoimmune and allergic responses by defined nematode molecules

Abstract

Keywords

UN SDGs

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