Mitochondrial organization and Ca2+ uptake

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Mitochondria may function as multiple separate organelles or as a single electrically coupled continuum to modulate changes in [Ca2+]c (cytoplasmic Ca2+ concentration) in various cell types. Mitochondria may also be tethered to the internal Ca2+ store or plasma membrane in particular parts of cells to facilitate the organelles modulation of local and global [Ca2+]c increases. Differences in the organization and positioning contributes significantly to the at times apparently contradictory reports on the way mitochondria modulate [Ca2+]c signals. In the present paper, we review the organization of mitochondria and the organelles role in Ca2+ signalling.
LanguageEnglish
Pages158-167
Number of pages10
JournalBiochemical Society Transactions
Volume40
Issue number1
DOIs
Publication statusPublished - 2012

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Mitochondria
Organelles
Cell membranes
Cell Membrane
Modulation

Keywords

  • cell types
  • Mitochondria
  • Ca2+

Cite this

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Mitochondrial organization and Ca2+ uptake. / Olson, Marnie L; Chalmers, Susan; McCarron, John G.

In: Biochemical Society Transactions, Vol. 40, No. 1, 2012, p. 158-167.

Research output: Contribution to journalArticle

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