Microfluidic systems for in situ formation of nylon 6,6 membranes

J. Gargiuli, E. Shapiro, H. Gulhane, G. Nair, D. Drikakis, P. Vadgama

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A microfluidics based, localised formation of nylon 6,6 membranes has been undertaken. The study demonstrates the feasibility of maintaining stable aqueous/organic interfaces for xylene within simple linear flow channels. Glass fabricated structures were used with adipoyl chloride and hexamethylenediamine in the organic and aqueous phases, respectively, in order to achieve nylon 6,6 interfacial polymerisation. Localised membrane formation was investigated in flow channels of different geometries over a wide range of flow rates (500–4000 μl/min), with Reynolds numbers ranging from 8.4 to 67.2. The results demonstrate that interfacial polymerisation occurs consistently over a wide range of flow rates and of flow entry angles for dual aqueous/organic solvent input. However, creation of uniform planar film structures required careful optimisation, and these were best achieved at 2000 μl/min with a flow entry angle of 45°. The resulting membranes had thicknesses in the range between 100 and 300 μm. Computational modelling of the aqueous/organic flow was performed in order to characterise flow stability and wall shear-stress patterns. The flow arrangement establishes a principle for the fabrication of micromembrane structures designed for low sample volume separation, where the forming reaction is a facile and rapid interfacial process
LanguageEnglish
Pages257-265
Number of pages9
JournalJournal of Membrane Science
Volume282
Issue number1-2
DOIs
Publication statusPublished - 5 Oct 2006

Fingerprint

Microfluidics
Nylon (trademark)
1,6-diaminohexane
Channel flow
membranes
Membranes
Polymerization
channel flow
Flow rate
entry
Xylenes
polymerization
flow velocity
Feasibility Studies
Xylene
flow stability
Organic solvents
Glass
Shear stress
xylene

Keywords

  • microfluidics
  • nylon
  • membranes
  • in situ formation
  • interfacial reaction

Cite this

Gargiuli, J., Shapiro, E., Gulhane, H., Nair, G., Drikakis, D., & Vadgama, P. (2006). Microfluidic systems for in situ formation of nylon 6,6 membranes. Journal of Membrane Science, 282(1-2), 257-265. https://doi.org/10.1016/j.memsci.2006.05.035
Gargiuli, J. ; Shapiro, E. ; Gulhane, H. ; Nair, G. ; Drikakis, D. ; Vadgama, P. / Microfluidic systems for in situ formation of nylon 6,6 membranes. In: Journal of Membrane Science. 2006 ; Vol. 282, No. 1-2. pp. 257-265.
@article{0b5709ad8c8a4d8882041ba495dbd5c4,
title = "Microfluidic systems for in situ formation of nylon 6,6 membranes",
abstract = "A microfluidics based, localised formation of nylon 6,6 membranes has been undertaken. The study demonstrates the feasibility of maintaining stable aqueous/organic interfaces for xylene within simple linear flow channels. Glass fabricated structures were used with adipoyl chloride and hexamethylenediamine in the organic and aqueous phases, respectively, in order to achieve nylon 6,6 interfacial polymerisation. Localised membrane formation was investigated in flow channels of different geometries over a wide range of flow rates (500–4000 μl/min), with Reynolds numbers ranging from 8.4 to 67.2. The results demonstrate that interfacial polymerisation occurs consistently over a wide range of flow rates and of flow entry angles for dual aqueous/organic solvent input. However, creation of uniform planar film structures required careful optimisation, and these were best achieved at 2000 μl/min with a flow entry angle of 45°. The resulting membranes had thicknesses in the range between 100 and 300 μm. Computational modelling of the aqueous/organic flow was performed in order to characterise flow stability and wall shear-stress patterns. The flow arrangement establishes a principle for the fabrication of micromembrane structures designed for low sample volume separation, where the forming reaction is a facile and rapid interfacial process",
keywords = "microfluidics, nylon, membranes, in situ formation, interfacial reaction",
author = "J. Gargiuli and E. Shapiro and H. Gulhane and G. Nair and D. Drikakis and P. Vadgama",
year = "2006",
month = "10",
day = "5",
doi = "10.1016/j.memsci.2006.05.035",
language = "English",
volume = "282",
pages = "257--265",
journal = "Journal of Membrane Science",
issn = "0376-7388",
number = "1-2",

}

Gargiuli, J, Shapiro, E, Gulhane, H, Nair, G, Drikakis, D & Vadgama, P 2006, 'Microfluidic systems for in situ formation of nylon 6,6 membranes' Journal of Membrane Science, vol. 282, no. 1-2, pp. 257-265. https://doi.org/10.1016/j.memsci.2006.05.035

Microfluidic systems for in situ formation of nylon 6,6 membranes. / Gargiuli, J.; Shapiro, E.; Gulhane, H.; Nair, G.; Drikakis, D.; Vadgama, P.

In: Journal of Membrane Science, Vol. 282, No. 1-2, 05.10.2006, p. 257-265.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Microfluidic systems for in situ formation of nylon 6,6 membranes

AU - Gargiuli, J.

AU - Shapiro, E.

AU - Gulhane, H.

AU - Nair, G.

AU - Drikakis, D.

AU - Vadgama, P.

PY - 2006/10/5

Y1 - 2006/10/5

N2 - A microfluidics based, localised formation of nylon 6,6 membranes has been undertaken. The study demonstrates the feasibility of maintaining stable aqueous/organic interfaces for xylene within simple linear flow channels. Glass fabricated structures were used with adipoyl chloride and hexamethylenediamine in the organic and aqueous phases, respectively, in order to achieve nylon 6,6 interfacial polymerisation. Localised membrane formation was investigated in flow channels of different geometries over a wide range of flow rates (500–4000 μl/min), with Reynolds numbers ranging from 8.4 to 67.2. The results demonstrate that interfacial polymerisation occurs consistently over a wide range of flow rates and of flow entry angles for dual aqueous/organic solvent input. However, creation of uniform planar film structures required careful optimisation, and these were best achieved at 2000 μl/min with a flow entry angle of 45°. The resulting membranes had thicknesses in the range between 100 and 300 μm. Computational modelling of the aqueous/organic flow was performed in order to characterise flow stability and wall shear-stress patterns. The flow arrangement establishes a principle for the fabrication of micromembrane structures designed for low sample volume separation, where the forming reaction is a facile and rapid interfacial process

AB - A microfluidics based, localised formation of nylon 6,6 membranes has been undertaken. The study demonstrates the feasibility of maintaining stable aqueous/organic interfaces for xylene within simple linear flow channels. Glass fabricated structures were used with adipoyl chloride and hexamethylenediamine in the organic and aqueous phases, respectively, in order to achieve nylon 6,6 interfacial polymerisation. Localised membrane formation was investigated in flow channels of different geometries over a wide range of flow rates (500–4000 μl/min), with Reynolds numbers ranging from 8.4 to 67.2. The results demonstrate that interfacial polymerisation occurs consistently over a wide range of flow rates and of flow entry angles for dual aqueous/organic solvent input. However, creation of uniform planar film structures required careful optimisation, and these were best achieved at 2000 μl/min with a flow entry angle of 45°. The resulting membranes had thicknesses in the range between 100 and 300 μm. Computational modelling of the aqueous/organic flow was performed in order to characterise flow stability and wall shear-stress patterns. The flow arrangement establishes a principle for the fabrication of micromembrane structures designed for low sample volume separation, where the forming reaction is a facile and rapid interfacial process

KW - microfluidics

KW - nylon

KW - membranes

KW - in situ formation

KW - interfacial reaction

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-33747812162&partnerID=40&md5=5d3a51740910e259cd3023dcb647f0c1

U2 - 10.1016/j.memsci.2006.05.035

DO - 10.1016/j.memsci.2006.05.035

M3 - Article

VL - 282

SP - 257

EP - 265

JO - Journal of Membrane Science

T2 - Journal of Membrane Science

JF - Journal of Membrane Science

SN - 0376-7388

IS - 1-2

ER -

Gargiuli J, Shapiro E, Gulhane H, Nair G, Drikakis D, Vadgama P. Microfluidic systems for in situ formation of nylon 6,6 membranes. Journal of Membrane Science. 2006 Oct 5;282(1-2):257-265. https://doi.org/10.1016/j.memsci.2006.05.035