Micro-/nano-patterning of DNA and rapid readout with SERS tags

Shuqing Sun, David Thompson, Ute Schmidt, Duncan Graham, Graham J. Leggett

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Hybridisation of oligonucleotide micro-and nano-structures, formed using far-and near-field optical lithography, with Raman dye-labelled silver nanoparticles functionalised with complementary oligonucleotides yields striking contrast, attributed to Raman "hot-spot'' formation, and enables rapid, convenient read-out by Raman microscopy.

Original languageEnglish
Pages (from-to)5292-5294
Number of pages3
JournalChemical Communications (London)
Volume46
Issue number29
DOIs
Publication statusPublished - 2010

Keywords

  • enhanced raman scattering
  • nanolithography
  • nanoparticles
  • lithography
  • nanoscale
  • molecules
  • beam

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