Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging

C. D. Saunter, S. Semprini, C. Buckley, J. Mullins, J. M. Girkin

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer diameter probe with a maximum tissue penetration depth of 15 mm specifically configured for eGFP imaging. Example results are given from imaging the pituitary gland of rats and zebrafish hearts with lateral resolution of 2.5 μm.
Original languageEnglish
Pages (from-to)1274-1278
Number of pages5
JournalBiomedical Optics Express
Volume3
Issue number6
DOIs
Publication statusPublished - 4 May 2012

Keywords

  • fluorescence microscopy
  • endoscopic imaging
  • scannerless probe

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