Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging

C. D. Saunter; S. Semprini; C. Buckley; J. Mullins; J. M. Girkin

doi:10.1364/BOE.3.001274

Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging

C. D. Saunter, S. Semprini, C. Buckley, J. Mullins, J. M. Girkin

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer diameter probe with a maximum tissue penetration depth of 15 mm specifically configured for eGFP imaging. Example results are given from imaging the pituitary gland of rats and zebrafish hearts with lateral resolution of 2.5 μm.

Original language	English
Pages (from-to)	1274-1278
Number of pages	5
Journal	Biomedical Optics Express
Volume	3
Issue number	6
DOIs	https://doi.org/10.1364/BOE.3.001274
Publication status	Published - 4 May 2012

Keywords

fluorescence microscopy
endoscopic imaging
scannerless probe

Access to Document

10.1364/BOE.3.001274

Cite this

@article{7411ef52f0e648c0b3ede6cecde036bb,

title = "Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging",

abstract = "In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer diameter probe with a maximum tissue penetration depth of 15 mm specifically configured for eGFP imaging. Example results are given from imaging the pituitary gland of rats and zebrafish hearts with lateral resolution of 2.5 μm.",

keywords = "fluorescence microscopy, endoscopic imaging, scannerless probe",

author = "Saunter, {C. D.} and S. Semprini and C. Buckley and J. Mullins and Girkin, {J. M.}",

year = "2012",

month = may,

day = "4",

doi = "10.1364/BOE.3.001274",

language = "English",

volume = "3",

pages = "1274--1278",

journal = "Biomedical Optics Express",

issn = "2156-7085",

publisher = "Optical Society of America",

number = "6",

}

TY - JOUR

T1 - Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging

AU - Saunter, C. D.

AU - Semprini, S.

AU - Buckley, C.

AU - Mullins, J.

AU - Girkin, J. M.

PY - 2012/5/4

Y1 - 2012/5/4

N2 - In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer diameter probe with a maximum tissue penetration depth of 15 mm specifically configured for eGFP imaging. Example results are given from imaging the pituitary gland of rats and zebrafish hearts with lateral resolution of 2.5 μm.

AB - In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer diameter probe with a maximum tissue penetration depth of 15 mm specifically configured for eGFP imaging. Example results are given from imaging the pituitary gland of rats and zebrafish hearts with lateral resolution of 2.5 μm.

KW - fluorescence microscopy

KW - endoscopic imaging

KW - scannerless probe

U2 - 10.1364/BOE.3.001274

DO - 10.1364/BOE.3.001274

M3 - Article

VL - 3

SP - 1274

EP - 1278

JO - Biomedical Optics Express

JF - Biomedical Optics Express

SN - 2156-7085

IS - 6

ER -

Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging

Abstract

Keywords

Access to Document

Fingerprint

Cite this