Magnetic particles coated with specific antibodies for substances of interest are introduced into a fluid sample. Over time and with agitation, the magnetic particles become attached to the substance of interest within the fluid. The fluid is then introduced to a magnetic field gradient provided between two magnets (1, 5). the resultant change to the magnetic filed between the magnets (1, 5) is determine by a Hall Effect device (3) or a plurality of Hall Effect devices (3). This enables the presence and/or concentration of the substance of interest in the sample to be determined.
|Publication status||Published - 2007|
- magnetic field gradient
- Hall Effect device
- magnetic particles
Connolly, P., Fuller, J., & Hall Effect Technologies Limited, P. Connolly, J. Fuller (Patent applicant) (2007). Method of determining the presence and/or concentration of substances of interest in fluids. (Patent No. WO/2005/124345).