Metastable hydrogels from aromatic dipeptides

M. P. Conte; N. Singh; I. R. Sasselli; B. Escuder; R. V. Ulijn

doi:10.1039/C6CC05821C

Metastable hydrogels from aromatic dipeptides

M. P. Conte, N. Singh, I. R. Sasselli, B. Escuder, R. V. Ulijn

Pure And Applied Chemistry

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Abstract

We demonstrate that the well-known self-assembling dipeptide diphenylalanine (FF) and its amidated derivative (FF-NH2) can form metastable hydrogels upon sonication of the dipeptide solutions. The hydrogels show instantaneous syneresis upon mechanical contact resulting in rapid expulsion of water and collapse into a semi-solid gel.

Original language	English
Pages (from-to)	13889-13892
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	96
Early online date	8 Nov 2016
DOIs	https://doi.org/10.1039/C6CC05821C
Publication status	E-pub ahead of print - 8 Nov 2016

Keywords

metastable hydrogels
self-assembling dipeptide
diphenylalanine

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10.1039/C6CC05821C

Conte-etal-CC-2016-Metastable-hydrogels-from-aromatic-dipeptidesAccepted author manuscript, 809 KB

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title = "Metastable hydrogels from aromatic dipeptides",

abstract = "We demonstrate that the well-known self-assembling dipeptide diphenylalanine (FF) and its amidated derivative (FF-NH2) can form metastable hydrogels upon sonication of the dipeptide solutions. The hydrogels show instantaneous syneresis upon mechanical contact resulting in rapid expulsion of water and collapse into a semi-solid gel.",

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AU - Conte, M. P.

AU - Singh, N.

AU - Sasselli, I. R.

AU - Escuder, B.

AU - Ulijn, R. V.

PY - 2016/11/8

Y1 - 2016/11/8

N2 - We demonstrate that the well-known self-assembling dipeptide diphenylalanine (FF) and its amidated derivative (FF-NH2) can form metastable hydrogels upon sonication of the dipeptide solutions. The hydrogels show instantaneous syneresis upon mechanical contact resulting in rapid expulsion of water and collapse into a semi-solid gel.

AB - We demonstrate that the well-known self-assembling dipeptide diphenylalanine (FF) and its amidated derivative (FF-NH2) can form metastable hydrogels upon sonication of the dipeptide solutions. The hydrogels show instantaneous syneresis upon mechanical contact resulting in rapid expulsion of water and collapse into a semi-solid gel.

KW - metastable hydrogels

KW - self-assembling dipeptide

KW - diphenylalanine

UR - http://pubs.rsc.org/en/journals/journal/cc

U2 - 10.1039/C6CC05821C

DO - 10.1039/C6CC05821C

M3 - Article

SN - 1359-7345

VL - 52

SP - 13889

EP - 13892

JO - Chemical Communications

JF - Chemical Communications

IS - 96

ER -

Metastable hydrogels from aromatic dipeptides

Abstract

Keywords

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