Melphalan and urinary estrogens

J.M. Anderson, J.K. Grant, G. Gettinby

Research output: Contribution to journalArticle

Abstract

A test of the concept of chemical suppression of ovarian function by cytotoxic drugs previously reported (Anderson et al., 1978, Br. J. Cancer, 37, 477) revealed no supportive evidence from follicular and luteal-phase measurements of plasma oestradiol (E2) in 6 premenopausal women prescribed repeated 5-day courses of melphalan after mastectomy for cancer. To circumvent the difficulties of frequent repeated blood sampling, 3 of these patients were studied in greater depth.
Original languageEnglish
Pages (from-to)314-315
Number of pages1
JournalBritish Journal of Cancer
Volume40
Issue number2
Publication statusPublished - 1979

Fingerprint

Melphalan
Estrogens
Chemical Phenomena
Follicular Phase
Luteal Phase
Mastectomy
Estradiol
Neoplasms
Pharmaceutical Preparations

Keywords

  • melphalan
  • urinary estrogens
  • mastectomy

Cite this

Anderson, J. M., Grant, J. K., & Gettinby, G. (1979). Melphalan and urinary estrogens. British Journal of Cancer, 40(2), 314-315.
Anderson, J.M. ; Grant, J.K. ; Gettinby, G. / Melphalan and urinary estrogens. In: British Journal of Cancer. 1979 ; Vol. 40, No. 2. pp. 314-315.
@article{9fee17bedb6f4f56ba79880b0b8e8a1a,
title = "Melphalan and urinary estrogens",
abstract = "A test of the concept of chemical suppression of ovarian function by cytotoxic drugs previously reported (Anderson et al., 1978, Br. J. Cancer, 37, 477) revealed no supportive evidence from follicular and luteal-phase measurements of plasma oestradiol (E2) in 6 premenopausal women prescribed repeated 5-day courses of melphalan after mastectomy for cancer. To circumvent the difficulties of frequent repeated blood sampling, 3 of these patients were studied in greater depth.",
keywords = "melphalan, urinary estrogens, mastectomy",
author = "J.M. Anderson and J.K. Grant and G. Gettinby",
year = "1979",
language = "English",
volume = "40",
pages = "314--315",
journal = "British Journal of Cancer",
issn = "0007-0920",
number = "2",

}

Anderson, JM, Grant, JK & Gettinby, G 1979, 'Melphalan and urinary estrogens', British Journal of Cancer, vol. 40, no. 2, pp. 314-315.

Melphalan and urinary estrogens. / Anderson, J.M.; Grant, J.K.; Gettinby, G.

In: British Journal of Cancer, Vol. 40, No. 2, 1979, p. 314-315.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Melphalan and urinary estrogens

AU - Anderson, J.M.

AU - Grant, J.K.

AU - Gettinby, G.

PY - 1979

Y1 - 1979

N2 - A test of the concept of chemical suppression of ovarian function by cytotoxic drugs previously reported (Anderson et al., 1978, Br. J. Cancer, 37, 477) revealed no supportive evidence from follicular and luteal-phase measurements of plasma oestradiol (E2) in 6 premenopausal women prescribed repeated 5-day courses of melphalan after mastectomy for cancer. To circumvent the difficulties of frequent repeated blood sampling, 3 of these patients were studied in greater depth.

AB - A test of the concept of chemical suppression of ovarian function by cytotoxic drugs previously reported (Anderson et al., 1978, Br. J. Cancer, 37, 477) revealed no supportive evidence from follicular and luteal-phase measurements of plasma oestradiol (E2) in 6 premenopausal women prescribed repeated 5-day courses of melphalan after mastectomy for cancer. To circumvent the difficulties of frequent repeated blood sampling, 3 of these patients were studied in greater depth.

KW - melphalan

KW - urinary estrogens

KW - mastectomy

UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010021/pdf/brjcancer00142-0118.pdf

M3 - Article

VL - 40

SP - 314

EP - 315

JO - British Journal of Cancer

JF - British Journal of Cancer

SN - 0007-0920

IS - 2

ER -

Anderson JM, Grant JK, Gettinby G. Melphalan and urinary estrogens. British Journal of Cancer. 1979;40(2):314-315.