Melphalan and urinary estrogens

J.M. Anderson, J.K. Grant, G. Gettinby

Research output: Contribution to journalArticlepeer-review


A test of the concept of chemical suppression of ovarian function by cytotoxic drugs previously reported (Anderson et al., 1978, Br. J. Cancer, 37, 477) revealed no supportive evidence from follicular and luteal-phase measurements of plasma oestradiol (E2) in 6 premenopausal women prescribed repeated 5-day courses of melphalan after mastectomy for cancer. To circumvent the difficulties of frequent repeated blood sampling, 3 of these patients were studied in greater depth.
Original languageEnglish
Pages (from-to)314-315
Number of pages1
JournalBritish Journal of Cancer
Issue number2
Publication statusPublished - 1979


  • melphalan
  • urinary estrogens
  • mastectomy


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