Mechanical characterisation of an FDM 3D printing process

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Abstract

3D printing (3DP) of pharmaceutical formulations via commercially available FDM pinters has gained interested in recent years, enabling personalisation of medicines. It also facilitates advanced control of the microstructure of the tablet core, permitting fine tuning of product release characteristics with a single formulation. In addition, the technology also offers a platform for Dose escalation studies employing a single formulation and single manufacturing step. The objective of this study was to perform a mechanical characterisation of the extrusion of pharmaceutically relevant feedstock material during an FDM process.

Keywords

  • 3D printing
  • mechanical testing
  • pharmaceutical formulation development
  • FDM (Fused Deposition Modeling)

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