Measuring storage and loss moduli using optical tweezers: Broadband microrheology

Manlio Tassieri, Graham M. Gibson, R. M. L. Evans, Alison M. Yao, Rebecca Warren, Miles J. Padgett, Jonathan M. Cooper

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)


We present an experimental procedure to perform broadband microrheological measurements with optical tweezers. A generalized Langevin equation is adopted to relate the time-dependent trajectory of a particle in an imposed flow to the frequency-dependent moduli of the complex fluid. This procedure allows us to measure the material linear viscoelastic properties across the widest frequency range achievable with optical tweezers.

Original languageEnglish
Pages (from-to)026308
Number of pages5
JournalPhysical Review E
Issue number2
Publication statusPublished - 18 Feb 2010


  • complex fluids
  • particle
  • rheology
  • force

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