Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

J. M. Milner, A. Patel, R. K. Davidson, T. E. Swingler, A. Desilets, D. A. Young, E. B. Kelso, S. T. Donell, T. E. Cawston, I. M. Clark, W. R. Ferrell, R. Plevin, J. C. Lockhart, R. Leduc, A. D. Rowan

Research output: Contribution to journalBook/Film/Article reviewpeer-review

65 Citations (Scopus)


Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).
Original languageEnglish
Pages (from-to)A40-A41
Number of pages2
JournalInternational Journal of Experimental Pathology
Issue number6
Publication statusPublished - Dec 2010


  • osteoarthritis
  • cartilage destruction
  • matriptase

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