Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

J. M. Milner, A. Patel, R. K. Davidson, T. E. Swingler, A. Desilets, D. A. Young, E. B. Kelso, S. T. Donell, T. E. Cawston, I. M. Clark, W. R. Ferrell, R. Plevin, J. C. Lockhart, R. Leduc, A. D. Rowan

Research output: Contribution to journalBook/Film/Article review

54 Citations (Scopus)

Abstract

Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).
Original languageEnglish
Pages (from-to)A40-A41
Number of pages2
JournalInternational Journal of Experimental Pathology
Volume91
Issue number6
DOIs
Publication statusPublished - Dec 2010

Fingerprint

Serine Proteases
Osteoarthritis
Cartilage
matriptase

Keywords

  • osteoarthritis
  • cartilage destruction
  • matriptase

Cite this

Milner, J. M. ; Patel, A. ; Davidson, R. K. ; Swingler, T. E. ; Desilets, A. ; Young, D. A. ; Kelso, E. B. ; Donell, S. T. ; Cawston, T. E. ; Clark, I. M. ; Ferrell, W. R. ; Plevin, R. ; Lockhart, J. C. ; Leduc, R. ; Rowan, A. D. / Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. In: International Journal of Experimental Pathology. 2010 ; Vol. 91, No. 6. pp. A40-A41.
@article{9979fa49bca74240a8a5a6f156d39cb9,
title = "Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis",
abstract = "Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).",
keywords = "osteoarthritis, cartilage destruction , matriptase",
author = "Milner, {J. M.} and A. Patel and Davidson, {R. K.} and Swingler, {T. E.} and A. Desilets and Young, {D. A.} and Kelso, {E. B.} and Donell, {S. T.} and Cawston, {T. E.} and Clark, {I. M.} and Ferrell, {W. R.} and R. Plevin and Lockhart, {J. C.} and R. Leduc and Rowan, {A. D.}",
year = "2010",
month = "12",
doi = "10.1111/j.1365-2613.2010.00741.x",
language = "English",
volume = "91",
pages = "A40--A41",
journal = "International Journal of Experimental Pathology",
issn = "0959-9673",
number = "6",

}

Milner, JM, Patel, A, Davidson, RK, Swingler, TE, Desilets, A, Young, DA, Kelso, EB, Donell, ST, Cawston, TE, Clark, IM, Ferrell, WR, Plevin, R, Lockhart, JC, Leduc, R & Rowan, AD 2010, 'Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis', International Journal of Experimental Pathology, vol. 91, no. 6, pp. A40-A41. https://doi.org/10.1111/j.1365-2613.2010.00741.x

Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. / Milner, J. M.; Patel, A.; Davidson, R. K.; Swingler, T. E.; Desilets, A.; Young, D. A.; Kelso, E. B.; Donell, S. T.; Cawston, T. E.; Clark, I. M.; Ferrell, W. R.; Plevin, R.; Lockhart, J. C.; Leduc, R.; Rowan, A. D.

In: International Journal of Experimental Pathology, Vol. 91, No. 6, 12.2010, p. A40-A41.

Research output: Contribution to journalBook/Film/Article review

TY - JOUR

T1 - Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

AU - Milner, J. M.

AU - Patel, A.

AU - Davidson, R. K.

AU - Swingler, T. E.

AU - Desilets, A.

AU - Young, D. A.

AU - Kelso, E. B.

AU - Donell, S. T.

AU - Cawston, T. E.

AU - Clark, I. M.

AU - Ferrell, W. R.

AU - Plevin, R.

AU - Lockhart, J. C.

AU - Leduc, R.

AU - Rowan, A. D.

PY - 2010/12

Y1 - 2010/12

N2 - Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).

AB - Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).

KW - osteoarthritis

KW - cartilage destruction

KW - matriptase

U2 - 10.1111/j.1365-2613.2010.00741.x

DO - 10.1111/j.1365-2613.2010.00741.x

M3 - Book/Film/Article review

VL - 91

SP - A40-A41

JO - International Journal of Experimental Pathology

JF - International Journal of Experimental Pathology

SN - 0959-9673

IS - 6

ER -