Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

J. M. Milner, A. Patel, R. K. Davidson, T. E. Swingler, A. Desilets, D. A. Young, E. B. Kelso, S. T. Donell, T. E. Cawston, I. M. Clark, W. R. Ferrell, R. Plevin, J. C. Lockhart, R. Leduc, A. D. Rowan

Research output: Contribution to journalBook/Film/Article reviewpeer-review

70 Citations (Scopus)

Abstract

Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).
Original languageEnglish
Pages (from-to)A40-A41
Number of pages2
JournalInternational Journal of Experimental Pathology
Volume91
Issue number6
DOIs
Publication statusPublished - Dec 2010

Keywords

  • osteoarthritis
  • cartilage destruction
  • matriptase

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