Mass measurement of inositol phosphates

S Palmer, M J Wakelam

Research output: Contribution to journalLiterature review

17 Citations (Scopus)

Abstract

This review summarises the methods available for the mass measurement of inositol phosphates, i.e., use of radioactive inositol lipid precursors, optical techniques, gas chromatography, mass spectrometry, nuclear magnetic resonance, fast atom bombardment and assays specific for Ins(1,4,5)P3. Examples of the use of each method, its sensitivity, advantages and drawbacks are given.

Original languageEnglish
Pages (from-to)239-246
Number of pages8
JournalBBA - Biochimica et Biophysica Acta
Volume1014
Issue number3
DOIs
Publication statusPublished - 14 Dec 1989

Keywords

  • animals
  • chromatography, gas
  • humans
  • inositol 1,4,5-trisphosphate
  • inositol phosphates
  • magnetic resonance spectroscopy
  • mass spectrometry
  • microchemistry
  • molecular weight
  • radioisotopes

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