Mapping the formation of eumelanin using coupled measurements

Philip Yip, Jens U Sutter

Research output: Contribution to conferencePoster

Abstract

Melanin plays a crucial role as a pigment all through the animal kingdom. Being a macromolecule just on the divide between an ordered crystalline or a purely amorphous form melanin has proven a challenge to structure-function analysis.

Melanin assembles from small molecules much like a jigsaw and much like in a jigsaw the fine detail quickly vanishes in the overall picture. With Melanin being first and foremost a photo-active molecule we focus on spectral properties for the characterization of its structure using linked measurements of excitation and emission to identify ‘areas of interest’ in the Excitation-Emission Matrix (EEM). We then probe for characteristic fluorescence lifetimes in the identified areas to track melanin building blocks through the formation pathway.

Conference

ConferenceFluoroFest
CountryUnited Kingdom
CityGlasgow
Period24/04/1726/04/17
Internet address

Fingerprint

melanin
pigments
macromolecules
excitation
animals
molecules
life (durability)
fluorescence
probes
matrices

Keywords

  • fluorescence
  • melanin
  • Excitation Emission Matrix (EEM)
  • bioengineeing

Cite this

Yip, P., & Sutter, J. U. (2017). Mapping the formation of eumelanin using coupled measurements. Poster session presented at FluoroFest , Glasgow, United Kingdom.
Yip, Philip ; Sutter, Jens U. / Mapping the formation of eumelanin using coupled measurements. Poster session presented at FluoroFest , Glasgow, United Kingdom.
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title = "Mapping the formation of eumelanin using coupled measurements",
abstract = "Melanin plays a crucial role as a pigment all through the animal kingdom. Being a macromolecule just on the divide between an ordered crystalline or a purely amorphous form melanin has proven a challenge to structure-function analysis. Melanin assembles from small molecules much like a jigsaw and much like in a jigsaw the fine detail quickly vanishes in the overall picture. With Melanin being first and foremost a photo-active molecule we focus on spectral properties for the characterization of its structure using linked measurements of excitation and emission to identify ‘areas of interest’ in the Excitation-Emission Matrix (EEM). We then probe for characteristic fluorescence lifetimes in the identified areas to track melanin building blocks through the formation pathway.",
keywords = "fluorescence, melanin, Excitation Emission Matrix (EEM), bioengineeing",
author = "Philip Yip and Sutter, {Jens U}",
year = "2017",
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day = "24",
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note = "FluoroFest ; Conference date: 24-04-2017 Through 26-04-2017",
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}

Yip, P & Sutter, JU 2017, 'Mapping the formation of eumelanin using coupled measurements' FluoroFest , Glasgow, United Kingdom, 24/04/17 - 26/04/17, .

Mapping the formation of eumelanin using coupled measurements. / Yip, Philip; Sutter, Jens U.

2017. Poster session presented at FluoroFest , Glasgow, United Kingdom.

Research output: Contribution to conferencePoster

TY - CONF

T1 - Mapping the formation of eumelanin using coupled measurements

AU - Yip, Philip

AU - Sutter, Jens U

PY - 2017/4/24

Y1 - 2017/4/24

N2 - Melanin plays a crucial role as a pigment all through the animal kingdom. Being a macromolecule just on the divide between an ordered crystalline or a purely amorphous form melanin has proven a challenge to structure-function analysis. Melanin assembles from small molecules much like a jigsaw and much like in a jigsaw the fine detail quickly vanishes in the overall picture. With Melanin being first and foremost a photo-active molecule we focus on spectral properties for the characterization of its structure using linked measurements of excitation and emission to identify ‘areas of interest’ in the Excitation-Emission Matrix (EEM). We then probe for characteristic fluorescence lifetimes in the identified areas to track melanin building blocks through the formation pathway.

AB - Melanin plays a crucial role as a pigment all through the animal kingdom. Being a macromolecule just on the divide between an ordered crystalline or a purely amorphous form melanin has proven a challenge to structure-function analysis. Melanin assembles from small molecules much like a jigsaw and much like in a jigsaw the fine detail quickly vanishes in the overall picture. With Melanin being first and foremost a photo-active molecule we focus on spectral properties for the characterization of its structure using linked measurements of excitation and emission to identify ‘areas of interest’ in the Excitation-Emission Matrix (EEM). We then probe for characteristic fluorescence lifetimes in the identified areas to track melanin building blocks through the formation pathway.

KW - fluorescence

KW - melanin

KW - Excitation Emission Matrix (EEM)

KW - bioengineeing

M3 - Poster

ER -

Yip P, Sutter JU. Mapping the formation of eumelanin using coupled measurements. 2017. Poster session presented at FluoroFest , Glasgow, United Kingdom.