Mapping the formation of eumelanin using coupled measurements

Philip Yip, Jens U Sutter

Research output: Contribution to conferencePoster

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Abstract

Melanin plays a crucial role as a pigment all through the animal kingdom. Being a macromolecule just on the divide between an ordered crystalline or a purely amorphous form melanin has proven a challenge to structure-function analysis.

Melanin assembles from small molecules much like a jigsaw and much like in a jigsaw the fine detail quickly vanishes in the overall picture. With Melanin being first and foremost a photo-active molecule we focus on spectral properties for the characterization of its structure using linked measurements of excitation and emission to identify ‘areas of interest’ in the Excitation-Emission Matrix (EEM). We then probe for characteristic fluorescence lifetimes in the identified areas to track melanin building blocks through the formation pathway.
Original languageEnglish
Publication statusPublished - 24 Apr 2017
EventFluoroFest - Village Hotel Club, Glasgow, United Kingdom
Duration: 24 Apr 201726 Apr 2017
http://www.fluorofest.org/

Conference

ConferenceFluoroFest
CountryUnited Kingdom
CityGlasgow
Period24/04/1726/04/17
Internet address

Keywords

  • fluorescence
  • melanin
  • Excitation Emission Matrix (EEM)
  • bioengineeing

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