Mammary gland involution and endocrine status in sows: effects of weaning age and lactation heat stress

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The impact of the duration of lactation and / or thermal stress on the endocrine status of sows and the concentrations of indicators of mammary involution at weaning was investigated. Twenty-eight primiparous sows were Landrace x Yorkshire housed to 21 (CTL) or 29 ° C (HS) in lactation. Half of the sows on each treatment were randomly assigned to a weaning at 22 days (W22: CTL, n = 7; HS, n = 8) and the other half at 44 days (W44: CTL, n = 6; HS , n = 7) postpartum. Litters were standardized to 10 or 11 piglets at days 2 and 9 piglets on day 23 of lactation. Samples of blood and milk were obtained on days -1, 1, 2 and 3 in relation to weaning (day 0). The concentrations of prolactin, IGF-I and lactose were measured in milk and blood and those of Na, K and IGFBP-5 were measured in milk. The composition of milk has also been determined. There was less of lactose (P <0001) and protein (P <0.05) in the milk of sows W44 compared to W22 milk of sows. The percentages of fat and dry matter in milk were lower (P <0.05) than with W44 to W22 days 2 and 3 post-weaning. There was less lactose in the milk of HS sows compared to sows milk CTL (P <0.05) on days 2 and 3. The day before weaning, the concentrations of prolactin in serum (P <0001) and milk (P <0.01) were lower and those of IGF-I in milk were higher (P = 0.01) with W44 with W22. The values of IGFBP-5 in milk were significantly lower (P <0001, more than 4 times), those of Na higher (P <0001) and K unchanged (P> 0.1) compared with W44 to W22. Post-weaning, a failure of epithelial junctions (increased Na and decreased K) was apparent one day earlier (2 vs. 3) with W44 than W22, and was more marked in group HS. In agreement, there was a transient increase in concentrations of lactose that same day in HS W44. The higher ratio Na / K compared with W44 to W22 attached to increasing concentrations of lactose, especially in HS, indicating a failure of mammary epithelial junctions with advancing lactation. The duration of lactation has an impact on milk components that are connected to the status of mammary involution in the sow and some of these effects are more apparent during a heat stress.
LanguageEnglish
Pages35-43
Number of pages8
JournalCanadian Journal of Animal Science
Volume87
Publication statusPublished - 2007

Fingerprint

Human Mammary Glands
Weaning
Lactation
mammary glands
lactose
sows
heat stress
Lactose
weaning
Milk
mammary involution
lactation
Hot Temperature
lactation duration
milk composition
HS 6
Breast
milk
piglets
insulin-like growth factor binding proteins

Keywords

  • mammary gland
  • involution
  • endocrine
  • sows
  • weaning
  • lactation
  • heat stress
  • biomedical sciences

Cite this

@article{1d06db11af244307a7a7f341cb93ee42,
title = "Mammary gland involution and endocrine status in sows: effects of weaning age and lactation heat stress",
abstract = "The impact of the duration of lactation and / or thermal stress on the endocrine status of sows and the concentrations of indicators of mammary involution at weaning was investigated. Twenty-eight primiparous sows were Landrace x Yorkshire housed to 21 (CTL) or 29 ° C (HS) in lactation. Half of the sows on each treatment were randomly assigned to a weaning at 22 days (W22: CTL, n = 7; HS, n = 8) and the other half at 44 days (W44: CTL, n = 6; HS , n = 7) postpartum. Litters were standardized to 10 or 11 piglets at days 2 and 9 piglets on day 23 of lactation. Samples of blood and milk were obtained on days -1, 1, 2 and 3 in relation to weaning (day 0). The concentrations of prolactin, IGF-I and lactose were measured in milk and blood and those of Na, K and IGFBP-5 were measured in milk. The composition of milk has also been determined. There was less of lactose (P <0001) and protein (P <0.05) in the milk of sows W44 compared to W22 milk of sows. The percentages of fat and dry matter in milk were lower (P <0.05) than with W44 to W22 days 2 and 3 post-weaning. There was less lactose in the milk of HS sows compared to sows milk CTL (P <0.05) on days 2 and 3. The day before weaning, the concentrations of prolactin in serum (P <0001) and milk (P <0.01) were lower and those of IGF-I in milk were higher (P = 0.01) with W44 with W22. The values of IGFBP-5 in milk were significantly lower (P <0001, more than 4 times), those of Na higher (P <0001) and K unchanged (P> 0.1) compared with W44 to W22. Post-weaning, a failure of epithelial junctions (increased Na and decreased K) was apparent one day earlier (2 vs. 3) with W44 than W22, and was more marked in group HS. In agreement, there was a transient increase in concentrations of lactose that same day in HS W44. The higher ratio Na / K compared with W44 to W22 attached to increasing concentrations of lactose, especially in HS, indicating a failure of mammary epithelial junctions with advancing lactation. The duration of lactation has an impact on milk components that are connected to the status of mammary involution in the sow and some of these effects are more apparent during a heat stress.",
keywords = "mammary gland, involution, endocrine, sows, weaning, lactation, heat stress, biomedical sciences",
author = "D.J. Flint",
year = "2007",
language = "English",
volume = "87",
pages = "35--43",
journal = "Canadian Journal of Animal Science",
issn = "0008-3984",

}

TY - JOUR

T1 - Mammary gland involution and endocrine status in sows: effects of weaning age and lactation heat stress

AU - Flint, D.J.

PY - 2007

Y1 - 2007

N2 - The impact of the duration of lactation and / or thermal stress on the endocrine status of sows and the concentrations of indicators of mammary involution at weaning was investigated. Twenty-eight primiparous sows were Landrace x Yorkshire housed to 21 (CTL) or 29 ° C (HS) in lactation. Half of the sows on each treatment were randomly assigned to a weaning at 22 days (W22: CTL, n = 7; HS, n = 8) and the other half at 44 days (W44: CTL, n = 6; HS , n = 7) postpartum. Litters were standardized to 10 or 11 piglets at days 2 and 9 piglets on day 23 of lactation. Samples of blood and milk were obtained on days -1, 1, 2 and 3 in relation to weaning (day 0). The concentrations of prolactin, IGF-I and lactose were measured in milk and blood and those of Na, K and IGFBP-5 were measured in milk. The composition of milk has also been determined. There was less of lactose (P <0001) and protein (P <0.05) in the milk of sows W44 compared to W22 milk of sows. The percentages of fat and dry matter in milk were lower (P <0.05) than with W44 to W22 days 2 and 3 post-weaning. There was less lactose in the milk of HS sows compared to sows milk CTL (P <0.05) on days 2 and 3. The day before weaning, the concentrations of prolactin in serum (P <0001) and milk (P <0.01) were lower and those of IGF-I in milk were higher (P = 0.01) with W44 with W22. The values of IGFBP-5 in milk were significantly lower (P <0001, more than 4 times), those of Na higher (P <0001) and K unchanged (P> 0.1) compared with W44 to W22. Post-weaning, a failure of epithelial junctions (increased Na and decreased K) was apparent one day earlier (2 vs. 3) with W44 than W22, and was more marked in group HS. In agreement, there was a transient increase in concentrations of lactose that same day in HS W44. The higher ratio Na / K compared with W44 to W22 attached to increasing concentrations of lactose, especially in HS, indicating a failure of mammary epithelial junctions with advancing lactation. The duration of lactation has an impact on milk components that are connected to the status of mammary involution in the sow and some of these effects are more apparent during a heat stress.

AB - The impact of the duration of lactation and / or thermal stress on the endocrine status of sows and the concentrations of indicators of mammary involution at weaning was investigated. Twenty-eight primiparous sows were Landrace x Yorkshire housed to 21 (CTL) or 29 ° C (HS) in lactation. Half of the sows on each treatment were randomly assigned to a weaning at 22 days (W22: CTL, n = 7; HS, n = 8) and the other half at 44 days (W44: CTL, n = 6; HS , n = 7) postpartum. Litters were standardized to 10 or 11 piglets at days 2 and 9 piglets on day 23 of lactation. Samples of blood and milk were obtained on days -1, 1, 2 and 3 in relation to weaning (day 0). The concentrations of prolactin, IGF-I and lactose were measured in milk and blood and those of Na, K and IGFBP-5 were measured in milk. The composition of milk has also been determined. There was less of lactose (P <0001) and protein (P <0.05) in the milk of sows W44 compared to W22 milk of sows. The percentages of fat and dry matter in milk were lower (P <0.05) than with W44 to W22 days 2 and 3 post-weaning. There was less lactose in the milk of HS sows compared to sows milk CTL (P <0.05) on days 2 and 3. The day before weaning, the concentrations of prolactin in serum (P <0001) and milk (P <0.01) were lower and those of IGF-I in milk were higher (P = 0.01) with W44 with W22. The values of IGFBP-5 in milk were significantly lower (P <0001, more than 4 times), those of Na higher (P <0001) and K unchanged (P> 0.1) compared with W44 to W22. Post-weaning, a failure of epithelial junctions (increased Na and decreased K) was apparent one day earlier (2 vs. 3) with W44 than W22, and was more marked in group HS. In agreement, there was a transient increase in concentrations of lactose that same day in HS W44. The higher ratio Na / K compared with W44 to W22 attached to increasing concentrations of lactose, especially in HS, indicating a failure of mammary epithelial junctions with advancing lactation. The duration of lactation has an impact on milk components that are connected to the status of mammary involution in the sow and some of these effects are more apparent during a heat stress.

KW - mammary gland

KW - involution

KW - endocrine

KW - sows

KW - weaning

KW - lactation

KW - heat stress

KW - biomedical sciences

UR - http://pubs.nrc-cnrc.gc.ca/aic-journals/cjas.html

M3 - Article

VL - 87

SP - 35

EP - 43

JO - Canadian Journal of Animal Science

T2 - Canadian Journal of Animal Science

JF - Canadian Journal of Animal Science

SN - 0008-3984

ER -