Abstract
A series of new Mg(II) amides featuring a bulky β-diketiminate backstop ligand, has been synthesised. These complexes are demonstrated to be excellent sources of nucleophilic amides that can participate in rapid C–F activation of several fluoroarenes at room temperature or using microwave assistance, leading to the installment of synthetically important C–N bonds via nucleophilic substitution.
Original language | English |
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Pages (from-to) | 4339-4342 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 55 |
Issue number | 30 |
DOIs | |
Publication status | Published - 13 Mar 2019 |
Keywords
- Fluorinated aromatic molecules
- medicinal chemistry
- Magnesium-mediated arylation
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Data for: "Magnesium-Mediated Arylation of Amines via C-F Bond Activation of Fluoroarenes"
Bole, L. (Contributor), Davin Cardona, L. (Contributor), Kennedy, A. (Contributor), McLellan, R. (Contributor) & Hevia, E. (Creator), University of Strathclyde, 19 Nov 2019
DOI: 10.15129/851ae734-bc89-418d-a7b1-ec99846c2ca5
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