LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation

Fiona McKenzie, Karen Faulds, Duncan Graham

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

Original languageEnglish
Pages (from-to)2367-2369
Number of pages3
JournalChemical Communications (London)
Issue number20
DOIs
Publication statusPublished - 28 May 2008

Keywords

  • oligonucleotide
  • optical detection
  • helix formation
  • polynucleotides

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