LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation

Fiona McKenzie, Karen Faulds, Duncan Graham

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

LanguageEnglish
Pages2367-2369
Number of pages3
JournalChemical Communications (London)
Issue number20
DOIs
Publication statusPublished - 28 May 2008

Fingerprint

Denaturation
Gold
Nanoparticles
DNA

Keywords

  • oligonucleotide
  • optical detection
  • helix formation
  • polynucleotides

Cite this

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title = "LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation",
abstract = "Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.",
keywords = "oligonucleotide, optical detection, helix formation, polynucleotides",
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LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation. / McKenzie, Fiona; Faulds, Karen; Graham, Duncan.

In: Chemical Communications (London), No. 20, 28.05.2008, p. 2367-2369.

Research output: Contribution to journalArticle

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AU - Faulds, Karen

AU - Graham, Duncan

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AB - Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

KW - oligonucleotide

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KW - polynucleotides

U2 - 10.1039/b802163e

DO - 10.1039/b802163e

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JO - Chemical Communications (London)

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