Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy

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Abstract

Live chicken egg embryos offer new opportunities for evaluation and continuous monitoring of tumour growth for in vivo studies compared to traditional rodent models. Here, we report the first use of surface enhanced Raman scattering (SERS) mapping and surface enhanced spatially offset Raman scattering (SESORS) for the detection and localisation of targeted gold nanoparticles in live chicken egg embryos bearing a glioblastoma tumour.
Original languageEnglish
Pages (from-to)3513-3517
Number of pages5
JournalAnalyst
Volume149
Issue number13
Early online date4 Jun 2024
DOIs
Publication statusE-pub ahead of print - 4 Jun 2024

Keywords

  • tumour model
  • Raman spectroscopy
  • chicken egg embryos
  • glioblastoma

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