Liquid-filled hard gelatin capsules: excipient/capsule compatibility studies

M. Kreiner; N. Thayne; D. Harkins; K. Rae; G. W. Halbert

Liquid-filled hard gelatin capsules: excipient/capsule compatibility studies

M. Kreiner, N. Thayne, D. Harkins, K. Rae, G. W. Halbert

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to conference › Poster › peer-review

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Abstract

Encapsulation of pharmaceutical formulations as liquids or semisolids, within hard gelatin capsules, presents an important oral dosage strategy for poorly water-soluble drugs, resulting in good bioavailability and reproducible drug absorption. In addition, this technology offers an inherently safer process than powder filled capsules and tablets for highly potent or cytotoxic drugs by avoiding dust generation. Here we present a compatibility study of hard gelatin capsules with common excipients in absence of active pharmaceutical.

Original language	English
Number of pages	1
Publication status	Published - 6 Sept 2016
Event	7th APS International PharmSci Conference - University of Strathclyde, Glasgow, United Kingdom Duration: 5 Sept 2016 → 7 Sept 2016 https://www.ukpharmsci.org/

Conference

Conference	7th APS International PharmSci Conference
Country/Territory	United Kingdom
City	Glasgow
Period	5/09/16 → 7/09/16
Internet address	https://www.ukpharmsci.org/

Keywords

encapsulation
gelatin capsules
drug absorption

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Kreiner-etal-APS2016-Liquid-filled-hard-gelatin-capsulesAccepted author manuscript, 2.05 MB

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title = "Liquid-filled hard gelatin capsules: excipient/capsule compatibility studies",

abstract = "Encapsulation of pharmaceutical formulations as liquids or semisolids, within hard gelatin capsules, presents an important oral dosage strategy for poorly water-soluble drugs, resulting in good bioavailability and reproducible drug absorption. In addition, this technology offers an inherently safer process than powder filled capsules and tablets for highly potent or cytotoxic drugs by avoiding dust generation. Here we present a compatibility study of hard gelatin capsules with common excipients in absence of active pharmaceutical. ",

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T1 - Liquid-filled hard gelatin capsules

T2 - 7th APS International PharmSci Conference

AU - Kreiner, M.

AU - Thayne, N.

AU - Harkins, D.

AU - Rae, K.

AU - Halbert, G. W.

PY - 2016/9/6

Y1 - 2016/9/6

N2 - Encapsulation of pharmaceutical formulations as liquids or semisolids, within hard gelatin capsules, presents an important oral dosage strategy for poorly water-soluble drugs, resulting in good bioavailability and reproducible drug absorption. In addition, this technology offers an inherently safer process than powder filled capsules and tablets for highly potent or cytotoxic drugs by avoiding dust generation. Here we present a compatibility study of hard gelatin capsules with common excipients in absence of active pharmaceutical.

AB - Encapsulation of pharmaceutical formulations as liquids or semisolids, within hard gelatin capsules, presents an important oral dosage strategy for poorly water-soluble drugs, resulting in good bioavailability and reproducible drug absorption. In addition, this technology offers an inherently safer process than powder filled capsules and tablets for highly potent or cytotoxic drugs by avoiding dust generation. Here we present a compatibility study of hard gelatin capsules with common excipients in absence of active pharmaceutical.

KW - encapsulation

KW - gelatin capsules

KW - drug absorption

UR - https://www.ukpharmsci.org/

M3 - Poster

Y2 - 5 September 2016 through 7 September 2016

ER -

Liquid-filled hard gelatin capsules: excipient/capsule compatibility studies

Abstract

Conference

Keywords

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