Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis

Elke Prasad; Ecaterina Bordos; Vaughan Langford; Mark Perkins; John Robertson; Gavin W. Halbert

Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis

Elke Prasad, Ecaterina Bordos, Vaughan Langford, Mark Perkins, John Robertson, Gavin W. Halbert

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to conference › Poster › peer-review

11 Downloads (Pure)

Abstract

3D printing (3DP) oral solid dose forms by Fused Filament Fabrication has gained increased interest in recent years. To facilitate efficient formulation and process development, some studies developed and implemented rheological and mechanical screening tests [1-3]. However, changes in the formulated polymeric system due to processing at elevated temperatures and shear have not been addressed. In this study, SIFT-MS Volatiles Organic Compound Analysis was employed to monitor a 3DP manufacturing process.

Original language	English
Number of pages	1
Publication status	Published - 22 Oct 2023
Event	AAPS 2023 PHARMSCI 360 - Orange County Convention Center, Orlando, United States Duration: 22 Oct 2023 → 25 Oct 2023 https://www.aaps.org/pharmsci/annual-meeting

Conference

Conference	AAPS 2023 PHARMSCI 360
Country/Territory	United States
City	Orlando
Period	22/10/23 → 25/10/23
Internet address	https://www.aaps.org/pharmsci/annual-meeting

Keywords

SIFT
volatile organic compound analysis
HME-3D printing
MS

Access to Document

Prasad-etal-AAPS-2023-Linking-3DP-manufacturing-with-SIFT-MSAccepted author manuscript, 642 KBLicence: CC BY 4.0

1 Presentation/Speech

The EPSRC Future Manufacturing Research HUB: 3D Printing MicroFactory
Prasad, E., Robertson, J. (Editor) & Halbert, G. (Editor), 2023.
Research output: Contribution to conference › Presentation/Speech

Cite this

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title = "Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis",

abstract = "3D printing (3DP) oral solid dose forms by Fused Filament Fabrication has gained increased interest in recent years. To facilitate efficient formulation and process development, some studies developed and implemented rheological and mechanical screening tests [1-3]. However, changes in the formulated polymeric system due to processing at elevated temperatures and shear have not been addressed. In this study, SIFT-MS Volatiles Organic Compound Analysis was employed to monitor a 3DP manufacturing process.",

keywords = "SIFT, volatile organic compound analysis, HME-3D printing, MS",

author = "Elke Prasad and Ecaterina Bordos and Vaughan Langford and Mark Perkins and John Robertson and Halbert, {Gavin W.}",

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TY - CONF

T1 - Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis

AU - Prasad, Elke

AU - Bordos, Ecaterina

AU - Langford, Vaughan

AU - Perkins, Mark

AU - Robertson, John

AU - Halbert, Gavin W.

PY - 2023/10/22

Y1 - 2023/10/22

N2 - 3D printing (3DP) oral solid dose forms by Fused Filament Fabrication has gained increased interest in recent years. To facilitate efficient formulation and process development, some studies developed and implemented rheological and mechanical screening tests [1-3]. However, changes in the formulated polymeric system due to processing at elevated temperatures and shear have not been addressed. In this study, SIFT-MS Volatiles Organic Compound Analysis was employed to monitor a 3DP manufacturing process.

AB - 3D printing (3DP) oral solid dose forms by Fused Filament Fabrication has gained increased interest in recent years. To facilitate efficient formulation and process development, some studies developed and implemented rheological and mechanical screening tests [1-3]. However, changes in the formulated polymeric system due to processing at elevated temperatures and shear have not been addressed. In this study, SIFT-MS Volatiles Organic Compound Analysis was employed to monitor a 3DP manufacturing process.

KW - SIFT

KW - volatile organic compound analysis

KW - HME-3D printing

KW - MS

M3 - Poster

T2 - AAPS 2023 PHARMSCI 360

Y2 - 22 October 2023 through 25 October 2023

ER -

Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis

Abstract

Conference

Keywords

Access to Document

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Research output

The EPSRC Future Manufacturing Research HUB: 3D Printing MicroFactory

Cite this