LC-MS analysis of oils of Monodora myristica and Monodora tenuifolia and isolation of a novel cyclopropane fatty acid

N.F. Al-Tannak, Ibrahim Khadra, N.P. Igoli, J.O. Igoli

Research output: Contribution to journalArticle

Abstract

Seeds of Monodora myristica and M. tenuifolia were extracted with hexane and the extractswere subjected to column chromatography, LC-MS and NMR analysis. In addition to masses of previously isolated compounds, other masses corresponding to unidentified compounds from the plants were detected. Using 2D NMR techniques, one of the fractions from M. tenuifolia was characterised as a novel 13-(2-butylcyclopropyl)-6,9-dodecadienoic acid. However, none of the compounds detected in LC-MS corresponded to the ones previously identified by GC-MS.
Original languageEnglish
JournalNatural Product Research
Early online date19 Jan 2019
DOIs
Publication statusE-pub ahead of print - 19 Jan 2019

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Hexanes
Chromatography
Seeds
Oils
Nuclear magnetic resonance
fatty acids
oils
Column chromatography
Acids
hexane
Seed
chromatography
acids
seeds
cyclopropane fatty acids
Monodora tenuifolia
Monodora myristica
methodology

Keywords

  • chromatography
  • phytochemical analysis
  • Nigeria

Cite this

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LC-MS analysis of oils of Monodora myristica and Monodora tenuifolia and isolation of a novel cyclopropane fatty acid. / Al-Tannak, N.F.; Khadra, Ibrahim; Igoli, N.P.; Igoli, J.O.

In: Natural Product Research, 19.01.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - LC-MS analysis of oils of Monodora myristica and Monodora tenuifolia and isolation of a novel cyclopropane fatty acid

AU - Al-Tannak, N.F.

AU - Khadra, Ibrahim

AU - Igoli, N.P.

AU - Igoli, J.O.

PY - 2019/1/19

Y1 - 2019/1/19

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AB - Seeds of Monodora myristica and M. tenuifolia were extracted with hexane and the extractswere subjected to column chromatography, LC-MS and NMR analysis. In addition to masses of previously isolated compounds, other masses corresponding to unidentified compounds from the plants were detected. Using 2D NMR techniques, one of the fractions from M. tenuifolia was characterised as a novel 13-(2-butylcyclopropyl)-6,9-dodecadienoic acid. However, none of the compounds detected in LC-MS corresponded to the ones previously identified by GC-MS.

KW - chromatography

KW - phytochemical analysis

KW - Nigeria

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JF - Natural Product Research

SN - 1478-6419

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