Laser generation of proton beams for the production of short-lived positron emitting radioisotopes

I. Spencer, K.W.D. Ledingham, R.P. Singhal, T. McCanny, P. McKenna, E.L. Clark, K. Krushelnick, M. Zepf, F.N. Beg, M. Tatarakis, A.E. Dangor, P.A. Norreys, R.J. Clarke, R.M. Allott, I.N. Ross

Research output: Contribution to journalArticle

155 Citations (Scopus)

Abstract

Protons of energies up to 37 MeV have been generated when ultra-intense lasers (up to 1020Wcm-2) interact with hydrogen containing solid targets. These protons can be used to induce nuclear reactions in secondary targets to produce β+-emitting nuclei of relevance to the nuclear medicine community, namely 11C and 13N via (p,n) and (p,α) reactions. Activities of the order of 200 kBq have been measured from a single laser pulse interacting with a thin solid target. The possibility of using ultra-intense lasers to produce commercial amounts of short-lived positron emitting sources for positron emission tomography (PET) is discussed.

Original languageEnglish
Pages (from-to)449-458
Number of pages10
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume183
Issue number3-4
DOIs
Publication statusPublished - 31 Oct 2001

Keywords

  • laser
  • nuclear
  • plasma
  • positron
  • proton

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