Laser generation of proton beams for the production of short-lived positron emitting radioisotopes

I. Spencer; K.W.D. Ledingham; R.P. Singhal; T. McCanny; P. McKenna; E.L. Clark; K. Krushelnick; M. Zepf; F.N. Beg; M. Tatarakis; A.E. Dangor; P.A. Norreys; R.J. Clarke; R.M. Allott; I.N. Ross

doi:10.1016/S0168-583X(01)00771-6

Laser generation of proton beams for the production of short-lived positron emitting radioisotopes

I. Spencer, K.W.D. Ledingham, R.P. Singhal, T. McCanny, P. McKenna, E.L. Clark, K. Krushelnick, M. Zepf, F.N. Beg, M. Tatarakis, A.E. Dangor, P.A. Norreys, R.J. Clarke, R.M. Allott, I.N. Ross

Research output: Contribution to journal › Article › peer-review

155 Citations (Scopus)

Abstract

Protons of energies up to 37 MeV have been generated when ultra-intense lasers (up to 10²⁰Wcm^-2) interact with hydrogen containing solid targets. These protons can be used to induce nuclear reactions in secondary targets to produce β⁺-emitting nuclei of relevance to the nuclear medicine community, namely ¹¹C and ¹³N via (p,n) and (p,α) reactions. Activities of the order of 200 kBq have been measured from a single laser pulse interacting with a thin solid target. The possibility of using ultra-intense lasers to produce commercial amounts of short-lived positron emitting sources for positron emission tomography (PET) is discussed.

Original language	English
Pages (from-to)	449-458
Number of pages	10
Journal	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume	183
Issue number	3-4
DOIs	https://doi.org/10.1016/S0168-583X(01)00771-6
Publication status	Published - 31 Oct 2001

Keywords

laser
nuclear
plasma
positron
proton

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Spencer, I., Ledingham, K. W. D., Singhal, R. P., McCanny, T., McKenna, P., Clark, E. L., Krushelnick, K., Zepf, M., Beg, F. N., Tatarakis, M., Dangor, A. E., Norreys, P. A., Clarke, R. J., Allott, R. M., & Ross, I. N. (2001). Laser generation of proton beams for the production of short-lived positron emitting radioisotopes. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 183(3-4), 449-458. https://doi.org/10.1016/S0168-583X(01)00771-6

Spencer, I. ; Ledingham, K.W.D. ; Singhal, R.P. ; McCanny, T. ; McKenna, P. ; Clark, E.L. ; Krushelnick, K. ; Zepf, M. ; Beg, F.N. ; Tatarakis, M. ; Dangor, A.E. ; Norreys, P.A. ; Clarke, R.J. ; Allott, R.M. ; Ross, I.N. / Laser generation of proton beams for the production of short-lived positron emitting radioisotopes. In: Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 2001 ; Vol. 183, No. 3-4. pp. 449-458.

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title = "Laser generation of proton beams for the production of short-lived positron emitting radioisotopes",

abstract = "Protons of energies up to 37 MeV have been generated when ultra-intense lasers (up to 1020Wcm-2) interact with hydrogen containing solid targets. These protons can be used to induce nuclear reactions in secondary targets to produce β+-emitting nuclei of relevance to the nuclear medicine community, namely 11C and 13N via (p,n) and (p,α) reactions. Activities of the order of 200 kBq have been measured from a single laser pulse interacting with a thin solid target. The possibility of using ultra-intense lasers to produce commercial amounts of short-lived positron emitting sources for positron emission tomography (PET) is discussed.",

keywords = "laser, nuclear, plasma, positron, proton",

author = "I. Spencer and K.W.D. Ledingham and R.P. Singhal and T. McCanny and P. McKenna and E.L. Clark and K. Krushelnick and M. Zepf and F.N. Beg and M. Tatarakis and A.E. Dangor and P.A. Norreys and R.J. Clarke and R.M. Allott and I.N. Ross",

year = "2001",

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doi = "10.1016/S0168-583X(01)00771-6",

language = "English",

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Spencer, I, Ledingham, KWD, Singhal, RP, McCanny, T , McKenna, P, Clark, EL, Krushelnick, K, Zepf, M, Beg, FN, Tatarakis, M, Dangor, AE, Norreys, PA, Clarke, RJ, Allott, RM & Ross, IN 2001, 'Laser generation of proton beams for the production of short-lived positron emitting radioisotopes', Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, vol. 183, no. 3-4, pp. 449-458. https://doi.org/10.1016/S0168-583X(01)00771-6

Laser generation of proton beams for the production of short-lived positron emitting radioisotopes. / Spencer, I.; Ledingham, K.W.D.; Singhal, R.P.; McCanny, T.; McKenna, P.; Clark, E.L.; Krushelnick, K.; Zepf, M.; Beg, F.N.; Tatarakis, M.; Dangor, A.E.; Norreys, P.A.; Clarke, R.J.; Allott, R.M.; Ross, I.N.

In: Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, Vol. 183, No. 3-4, 31.10.2001, p. 449-458.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Laser generation of proton beams for the production of short-lived positron emitting radioisotopes

AU - Spencer, I.

AU - Ledingham, K.W.D.

AU - Singhal, R.P.

AU - McCanny, T.

AU - McKenna, P.

AU - Clark, E.L.

AU - Krushelnick, K.

AU - Zepf, M.

AU - Beg, F.N.

AU - Tatarakis, M.

AU - Dangor, A.E.

AU - Norreys, P.A.

AU - Clarke, R.J.

AU - Allott, R.M.

AU - Ross, I.N.

PY - 2001/10/31

Y1 - 2001/10/31

N2 - Protons of energies up to 37 MeV have been generated when ultra-intense lasers (up to 1020Wcm-2) interact with hydrogen containing solid targets. These protons can be used to induce nuclear reactions in secondary targets to produce β+-emitting nuclei of relevance to the nuclear medicine community, namely 11C and 13N via (p,n) and (p,α) reactions. Activities of the order of 200 kBq have been measured from a single laser pulse interacting with a thin solid target. The possibility of using ultra-intense lasers to produce commercial amounts of short-lived positron emitting sources for positron emission tomography (PET) is discussed.

AB - Protons of energies up to 37 MeV have been generated when ultra-intense lasers (up to 1020Wcm-2) interact with hydrogen containing solid targets. These protons can be used to induce nuclear reactions in secondary targets to produce β+-emitting nuclei of relevance to the nuclear medicine community, namely 11C and 13N via (p,n) and (p,α) reactions. Activities of the order of 200 kBq have been measured from a single laser pulse interacting with a thin solid target. The possibility of using ultra-intense lasers to produce commercial amounts of short-lived positron emitting sources for positron emission tomography (PET) is discussed.

KW - laser

KW - nuclear

KW - plasma

KW - positron

KW - proton

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JO - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

JF - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

SN - 0168-583X

IS - 3-4

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