Label-free pathogen detection with sensor chips assembled from peptide nanotubes

Roberto De La Rica, Ernest Mendoza, Laura Lechuga, Hiroshi Matsui

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

A robust viral sensor was developed by bridging a pair of gold electrodes with antibody-coated peptide nanotubes. The nanotubes concentrated the target virus on their surface by molecular recognition between the antibody and the virus (see picture). The nanotubes fit perfectly within the electric field line distribution to enable the extremely sensitive impedimetric detection of viral particles.
LanguageEnglish
Pages9752–9755
Number of pages4
JournalAngewandte Chemie International Edition
Volume47
Issue number50
Early online date6 Nov 2008
DOIs
Publication statusPublished - 1 Dec 2008

Fingerprint

Peptide Nanotubes
Nanotubes
pathogens
peptides
nanotubes
chips
viruses
Viruses
antibodies
Antibodies
sensors
Gold
Virion
Electrodes
gold
electrodes
electric fields

Keywords

  • peptide
  • label-free
  • pathogen detection
  • sensor chips
  • sensors
  • viruses
  • bionanotechnology
  • peptide nanotubes
  • self-assembly

Cite this

De La Rica, Roberto ; Mendoza, Ernest ; Lechuga, Laura ; Matsui, Hiroshi. / Label-free pathogen detection with sensor chips assembled from peptide nanotubes. In: Angewandte Chemie International Edition. 2008 ; Vol. 47, No. 50. pp. 9752–9755.
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Label-free pathogen detection with sensor chips assembled from peptide nanotubes. / De La Rica, Roberto; Mendoza, Ernest; Lechuga, Laura; Matsui, Hiroshi.

In: Angewandte Chemie International Edition, Vol. 47, No. 50, 01.12.2008, p. 9752–9755.

Research output: Contribution to journalArticle

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