Knowledge, attitudes and perspective on adverse drug reaction reporting in a public sector hospital in South Africa: baseline analysis

Antionette Terblanche, Johanna Meyer, Brian Godman, Robert Summers

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background and aims: Adverse drug reactions (ADRs) can cause significant harm in patients; however, ADRs are under-reported in many countries, including South Africa, where evidence of a pharmacovigilance (PV) system to monitor and manage ADRs is a requirement for compliance with norms and standards for quality healthcare delivery. We conducted an analysis amongst health care professionals (HCPs) at Sebokeng Hospital to assess the situation there. Methods: Data were collected using a structured self-administered questionnaire, targeting all medical practitioners, nurses, pharmacists and pharmacist assistants in the hospital. Current procedures for reporting of ADRs were documented. Records were reviewed to determine the number of ADR reports submitted for the 18-month period prior to the study. Data were analysed with SAS. Ethical clearance was obtained. Results: The questionnaire was completed by 132 HCPs (nurses: 58.3%; medical practitioners: 23.5%; pharmacist assistants: 11.4%; pharmacists: 6.8%). The vast majority indicated ADR reporting is necessary (96.2%) and their professional obligation (89.4%). Only 18.9% were aware of an existing PV system in the hospital, 15.2% had an ADR form available and 18.9% knew to whom the form should be submitted. The vast majority had never reported an ADR, had never received training in PV, but wanted training on ADR reporting. Factors discouraging ADR reporting included not knowing how to report them (53.8%), lack of time (37.1%), additional work load (22.0%), uncertainty about the outcome of reporting (32.6%), and lack of confidence to discuss ADRs with colleagues (22.0%). Only 2.3% knew how many ADRs were reported, that ADRs are discussed by a committee (6.1%) and that internal feedback is received on reported ADRs (6.1%). Conclusion: There is an extensive need in Sebokeng Hospital for training on ADR reporting and implementation of systems to facilitate relevant processes; a need which may also exist in other public hospitals in South Africa.
LanguageEnglish
Number of pages12
JournalHospital Practice
Early online date15 Sep 2017
DOIs
Publication statusE-pub ahead of print - 15 Sep 2017

Fingerprint

Public Sector
Public Hospitals
South Africa
Drug-Related Side Effects and Adverse Reactions
Pharmacovigilance
Pharmacists
Delivery of Health Care
Adverse Drug Reaction Reporting Systems
Patient Harm
Nurse Practitioners
Quality of Health Care
Workload
Uncertainty

Keywords

  • pharmacovigilance
  • adverse drug reactions
  • healthcare professionals
  • hospitals
  • training
  • South Africa

Cite this

@article{2ac5aa42bbff443cb67d508595e8dda2,
title = "Knowledge, attitudes and perspective on adverse drug reaction reporting in a public sector hospital in South Africa: baseline analysis",
abstract = "Background and aims: Adverse drug reactions (ADRs) can cause significant harm in patients; however, ADRs are under-reported in many countries, including South Africa, where evidence of a pharmacovigilance (PV) system to monitor and manage ADRs is a requirement for compliance with norms and standards for quality healthcare delivery. We conducted an analysis amongst health care professionals (HCPs) at Sebokeng Hospital to assess the situation there. Methods: Data were collected using a structured self-administered questionnaire, targeting all medical practitioners, nurses, pharmacists and pharmacist assistants in the hospital. Current procedures for reporting of ADRs were documented. Records were reviewed to determine the number of ADR reports submitted for the 18-month period prior to the study. Data were analysed with SAS. Ethical clearance was obtained. Results: The questionnaire was completed by 132 HCPs (nurses: 58.3{\%}; medical practitioners: 23.5{\%}; pharmacist assistants: 11.4{\%}; pharmacists: 6.8{\%}). The vast majority indicated ADR reporting is necessary (96.2{\%}) and their professional obligation (89.4{\%}). Only 18.9{\%} were aware of an existing PV system in the hospital, 15.2{\%} had an ADR form available and 18.9{\%} knew to whom the form should be submitted. The vast majority had never reported an ADR, had never received training in PV, but wanted training on ADR reporting. Factors discouraging ADR reporting included not knowing how to report them (53.8{\%}), lack of time (37.1{\%}), additional work load (22.0{\%}), uncertainty about the outcome of reporting (32.6{\%}), and lack of confidence to discuss ADRs with colleagues (22.0{\%}). Only 2.3{\%} knew how many ADRs were reported, that ADRs are discussed by a committee (6.1{\%}) and that internal feedback is received on reported ADRs (6.1{\%}). Conclusion: There is an extensive need in Sebokeng Hospital for training on ADR reporting and implementation of systems to facilitate relevant processes; a need which may also exist in other public hospitals in South Africa.",
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Knowledge, attitudes and perspective on adverse drug reaction reporting in a public sector hospital in South Africa : baseline analysis. / Terblanche, Antionette ; Meyer, Johanna; Godman, Brian; Summers, Robert .

In: Hospital Practice, 15.09.2017.

Research output: Contribution to journalArticle

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T1 - Knowledge, attitudes and perspective on adverse drug reaction reporting in a public sector hospital in South Africa

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AB - Background and aims: Adverse drug reactions (ADRs) can cause significant harm in patients; however, ADRs are under-reported in many countries, including South Africa, where evidence of a pharmacovigilance (PV) system to monitor and manage ADRs is a requirement for compliance with norms and standards for quality healthcare delivery. We conducted an analysis amongst health care professionals (HCPs) at Sebokeng Hospital to assess the situation there. Methods: Data were collected using a structured self-administered questionnaire, targeting all medical practitioners, nurses, pharmacists and pharmacist assistants in the hospital. Current procedures for reporting of ADRs were documented. Records were reviewed to determine the number of ADR reports submitted for the 18-month period prior to the study. Data were analysed with SAS. Ethical clearance was obtained. Results: The questionnaire was completed by 132 HCPs (nurses: 58.3%; medical practitioners: 23.5%; pharmacist assistants: 11.4%; pharmacists: 6.8%). The vast majority indicated ADR reporting is necessary (96.2%) and their professional obligation (89.4%). Only 18.9% were aware of an existing PV system in the hospital, 15.2% had an ADR form available and 18.9% knew to whom the form should be submitted. The vast majority had never reported an ADR, had never received training in PV, but wanted training on ADR reporting. Factors discouraging ADR reporting included not knowing how to report them (53.8%), lack of time (37.1%), additional work load (22.0%), uncertainty about the outcome of reporting (32.6%), and lack of confidence to discuss ADRs with colleagues (22.0%). Only 2.3% knew how many ADRs were reported, that ADRs are discussed by a committee (6.1%) and that internal feedback is received on reported ADRs (6.1%). Conclusion: There is an extensive need in Sebokeng Hospital for training on ADR reporting and implementation of systems to facilitate relevant processes; a need which may also exist in other public hospitals in South Africa.

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