ITRF/LhARA Conceptual Design Report

H Ahmed; Matthew Alderton; R.A. Amos; D.O. Ariyanto; C. J. Baker; J. Bamber; J. Bebbington; W. Bertsche; Robert Bingham; N. Bliss; E Boella; S. Boogert; M. Borghesi; R. Buckley; Philip Nicholas Burrows; G. Casati; Mike Charlton; X. Chen; J. Clarke; B. T. Cox; G. Cox; Titus-Stephan Dascalu; Ewan Dolier; M. Dosanjh; N. P. Dover; C. Dyson; S. Eriksson; A. Fernandez-Rodriguez; S. Gerlach; A. Giaccia; S. Gibson; A. Goulden; Ross Gray; S. Green; T. Greenshaw; S. Griffiths; D Gujral; H. C. Hall; C. Hardiman; E.J. Harris; C. Hill; P.R. Hobson; R.P. Hugtenburg; A. Isaac; M. Johnson; W.G. Jones; P.J. Jurj; Martin King; A. Knoll; N. Kumar; T.J. Kuo; A. Kurup; J.B. Lagrange; J. Lascaud; A.M. Lombardi; Kenneth R. Long; W.G. Luk; S. Lyu; T.A.M. Masilela; P. Matthews; M. Maxouti; J.M. McGarrigle; Paul McKenna; R. McLauchlan; I. McNeish; E. Melia; K. Middleman; Z. Najmudin; M. Noro; S.R. O’Neill; L. Obst-Huebl; U. Oelfke; H. Owen; Charlotte  Palmer; F. Parambil; K. Parodi; J.L. Parsons; J. Pasternak; M. Patel; R. Pattathil; M. Pereira; H. Poptani; Y. Prezado; P. Price; T. Price; K.M. Prise; C. Pugh; P. Ratoff; R. Razak; F. Romano; P. Ruksasakchai; M. Sabate-Gilarte; Z. Sadhur; A. Sandhu; G. Schettino; J. Schreiber; W. Shields; B. Smart; R.A. Smith; A.M. Snijders; D. Spiers; S. Tantawi; J.W.G. Thomason; Ben Torrance; S. Towe; T. Underwood; D.P. van der Werf; A. Vick; A. Vikhoreva; P. Weightman; C.P. Welsch; Colin Whyte; Robbie Wilson; N. Zakhir

ITRF/LhARA Conceptual Design Report

H Ahmed
, Matthew Alderton
, R.A. Amos
, D.O. Ariyanto
, C. J. Baker
, J. Bamber
, J. Bebbington
, W. Bertsche
, Robert Bingham
, N. Bliss
, E Boella
, S. Boogert
, M. Borghesi
, R. Buckley
, Philip Nicholas Burrows
, G. Casati
, Mike Charlton
, X. Chen
, J. Clarke
, B. T. Cox

G. Cox, Titus-Stephan Dascalu, Ewan Dolier, M. Dosanjh, N. P. Dover, C. Dyson, S. Eriksson, A. Fernandez-Rodriguez, S. Gerlach, A. Giaccia, S. Gibson, A. Goulden, Ross Gray, S. Green, T. Greenshaw, S. Griffiths, D Gujral, H. C. Hall, C. Hardiman, E.J. Harris, C. Hill, P.R. Hobson, R.P. Hugtenburg, A. Isaac, M. Johnson, W.G. Jones, P.J. Jurj, Martin King, A. Knoll, N. Kumar, T.J. Kuo, A. Kurup, J.B. Lagrange, J. Lascaud, A.M. Lombardi, Kenneth R. Long, W.G. Luk, S. Lyu, T.A.M. Masilela, P. Matthews, M. Maxouti, J.M. McGarrigle, Paul McKenna, R. McLauchlan, I. McNeish, E. Melia, K. Middleman, Z. Najmudin, M. Noro, S.R. O’Neill, L. Obst-Huebl, U. Oelfke, H. Owen, Charlotte Palmer, F. Parambil, K. Parodi, J.L. Parsons, J. Pasternak, M. Patel, R. Pattathil, M. Pereira, H. Poptani, Y. Prezado, P. Price, T. Price, K.M. Prise, C. Pugh, P. Ratoff, R. Razak, F. Romano, P. Ruksasakchai, M. Sabate-Gilarte, Z. Sadhur, A. Sandhu, G. Schettino, J. Schreiber, W. Shields, B. Smart, R.A. Smith, A.M. Snijders, D. Spiers, S. Tantawi, J.W.G. Thomason, Ben Torrance, S. Towe, T. Underwood, D.P. van der Werf, A. Vick, A. Vikhoreva, P. Weightman, C.P. Welsch, Colin Whyte, Robbie Wilson, N. Zakhir

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Abstract

This document, the principal deliverable of the Preliminary Activity, presents the conceptual design for LhARA to serve the ITRF. The conceptual design of the accelerator facility is presented in Chapter 2. Comparison of the laser-hybrid solution with the conventional alternatives has allowed the LhARA approach to be confirmed as the baseline design [15]. The conceptual design for the facility is shown in figure 1.

Original language	English
Number of pages	275
Publication status	Published - Feb 2026

Funding

The work described here was made possible by a grant from the UK Research and Innovation Infrastructure Fund. Substantial additional support was provided by STFC, CNRS, and the institutes that make up the LhARA collaboration. We are grateful for the support of the STFC Project Sponsor, M. Noro, the ITRF Project Board, the ITRF Advisory Committee and its Chair, N. Burnett.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

radiation therapy
cancer treatment
radiation biology and medicine
pulsed laser

Access to Document

ITRF-LhARA-Conceptual-Design-Report-2026Final published version, 77.9 MBLicence: CC BY 4.0

Cite this

@book{a0d22820172d4a97a4732c9c34d094aa,

title = "ITRF/LhARA Conceptual Design Report",

abstract = "This document, the principal deliverable of the Preliminary Activity, presents the conceptual design for LhARA to serve the ITRF. The conceptual design of the accelerator facility is presented in Chapter 2. Comparison of the laser-hybrid solution with the conventional alternatives has allowed the LhARA approach to be confirmed as the baseline design [15]. The conceptual design for the facility is shown in figure 1.",

keywords = "radiation therapy, cancer treatment, radiation biology and medicine, pulsed laser",

author = "H Ahmed and Matthew Alderton and R.A. Amos and D.O. Ariyanto and Baker, \{C. J.\} and J. Bamber and J. Bebbington and W. Bertsche and Robert Bingham and N. Bliss and E Boella and S. Boogert and M. Borghesi and R. Buckley and Burrows, \{Philip Nicholas\} and G. Casati and Mike Charlton and X. Chen and J. Clarke and Cox, \{B. T.\} and G. Cox and Titus-Stephan Dascalu and Ewan Dolier and M. Dosanjh and Dover, \{N. P.\} and C. Dyson and S. Eriksson and A. Fernandez-Rodriguez and S. Gerlach and A. Giaccia and S. Gibson and A. Goulden and Ross Gray and S. Green and T. Greenshaw and S. Griffiths and D Gujral and Hall, \{H. C.\} and C. Hardiman and E.J. Harris and C. Hill and P.R. Hobson and R.P. Hugtenburg and A. Isaac and M. Johnson and W.G. Jones and P.J. Jurj and Martin King and A. Knoll and N. Kumar and T.J. Kuo and A. Kurup and J.B. Lagrange and J. Lascaud and A.M. Lombardi and Long, \{Kenneth R.\} and W.G. Luk and S. Lyu and T.A.M. Masilela and P. Matthews and M. Maxouti and J.M. McGarrigle and Paul McKenna and R. McLauchlan and I. McNeish and E. Melia and K. Middleman and Z. Najmudin and M. Noro and S.R. O{\textquoteright}Neill and L. Obst-Huebl and U. Oelfke and H. Owen and Charlotte Palmer and F. Parambil and K. Parodi and J.L. Parsons and J. Pasternak and M. Patel and R. Pattathil and M. Pereira and H. Poptani and Y. Prezado and P. Price and T. Price and K.M. Prise and C. Pugh and P. Ratoff and R. Razak and F. Romano and P. Ruksasakchai and M. Sabate-Gilarte and Z. Sadhur and A. Sandhu and G. Schettino and J. Schreiber and W. Shields and B. Smart and R.A. Smith and A.M. Snijders and D. Spiers and S. Tantawi and J.W.G. Thomason and Ben Torrance and S. Towe and T. Underwood and \{van der Werf\}, D.P. and A. Vick and A. Vikhoreva and P. Weightman and C.P. Welsch and Colin Whyte and Robbie Wilson and N. Zakhir",

year = "2026",

month = feb,

language = "English",

}

Ahmed, H, Alderton, M, Amos, RA, Ariyanto, DO, Baker, CJ, Bamber, J, Bebbington, J, Bertsche, W, Bingham, R, Bliss, N, Boella, E, Boogert, S, Borghesi, M, Buckley, R, Burrows, PN, Casati, G, Charlton, M, Chen, X, Clarke, J, Cox, BT, Cox, G, Dascalu, T-S, Dolier, E, Dosanjh, M, Dover, NP, Dyson, C, Eriksson, S, Fernandez-Rodriguez, A, Gerlach, S, Giaccia, A, Gibson, S, Goulden, A, Gray, R, Green, S, Greenshaw, T, Griffiths, S, Gujral, D, Hall, HC, Hardiman, C, Harris, EJ, Hill, C, Hobson, PR, Hugtenburg, RP, Isaac, A, Johnson, M, Jones, WG, Jurj, PJ, King, M, Knoll, A, Kumar, N, Kuo, TJ, Kurup, A, Lagrange, JB, Lascaud, J, Lombardi, AM, Long, KR, Luk, WG, Lyu, S, Masilela, TAM, Matthews, P, Maxouti, M, McGarrigle, JM, McKenna, P, McLauchlan, R, McNeish, I, Melia, E, Middleman, K, Najmudin, Z, Noro, M, O’Neill, SR, Obst-Huebl, L, Oelfke, U, Owen, H, Palmer, C, Parambil, F, Parodi, K, Parsons, JL, Pasternak, J, Patel, M, Pattathil, R, Pereira, M, Poptani, H, Prezado, Y, Price, P, Price, T, Prise, KM, Pugh, C, Ratoff, P, Razak, R, Romano, F, Ruksasakchai, P, Sabate-Gilarte, M, Sadhur, Z, Sandhu, A, Schettino, G, Schreiber, J, Shields, W, Smart, B, Smith, RA, Snijders, AM, Spiers, D, Tantawi, S, Thomason, JWG, Torrance, B, Towe, S, Underwood, T, van der Werf, DP, Vick, A, Vikhoreva, A, Weightman, P, Welsch, CP, Whyte, C , Wilson, R & Zakhir, N 2026, ITRF/LhARA Conceptual Design Report.

TY - BOOK

T1 - ITRF/LhARA Conceptual Design Report

AU - Ahmed, H

AU - Alderton, Matthew

AU - Amos, R.A.

AU - Ariyanto, D.O.

AU - Baker, C. J.

AU - Bamber, J.

AU - Bebbington, J.

AU - Bertsche, W.

AU - Bingham, Robert

AU - Bliss, N.

AU - Boella, E

AU - Boogert, S.

AU - Borghesi, M.

AU - Buckley, R.

AU - Burrows, Philip Nicholas

AU - Casati, G.

AU - Charlton, Mike

AU - Chen, X.

AU - Clarke, J.

AU - Cox, B. T.

AU - Cox, G.

AU - Dascalu, Titus-Stephan

AU - Dolier, Ewan

AU - Dosanjh, M.

AU - Dover, N. P.

AU - Dyson, C.

AU - Eriksson, S.

AU - Fernandez-Rodriguez, A.

AU - Gerlach, S.

AU - Giaccia, A.

AU - Gibson, S.

AU - Goulden, A.

AU - Gray, Ross

AU - Green, S.

AU - Greenshaw, T.

AU - Griffiths, S.

AU - Gujral, D

AU - Hall, H. C.

AU - Hardiman, C.

AU - Harris, E.J.

AU - Hill, C.

AU - Hobson, P.R.

AU - Hugtenburg, R.P.

AU - Isaac, A.

AU - Johnson, M.

AU - Jones, W.G.

AU - Jurj, P.J.

AU - King, Martin

AU - Knoll, A.

AU - Kumar, N.

AU - Kuo, T.J.

AU - Kurup, A.

AU - Lagrange, J.B.

AU - Lascaud, J.

AU - Lombardi, A.M.

AU - Long, Kenneth R.

AU - Luk, W.G.

AU - Lyu, S.

AU - Masilela, T.A.M.

AU - Matthews, P.

AU - Maxouti, M.

AU - McGarrigle, J.M.

AU - McKenna, Paul

AU - McLauchlan, R.

AU - McNeish, I.

AU - Melia, E.

AU - Middleman, K.

AU - Najmudin, Z.

AU - Noro, M.

AU - O’Neill, S.R.

AU - Obst-Huebl, L.

AU - Oelfke, U.

AU - Owen, H.

AU - Palmer, Charlotte

AU - Parambil, F.

AU - Parodi, K.

AU - Parsons, J.L.

AU - Pasternak, J.

AU - Patel, M.

AU - Pattathil, R.

AU - Pereira, M.

AU - Poptani, H.

AU - Prezado, Y.

AU - Price, P.

AU - Price, T.

AU - Prise, K.M.

AU - Pugh, C.

AU - Ratoff, P.

AU - Razak, R.

AU - Romano, F.

AU - Ruksasakchai, P.

AU - Sabate-Gilarte, M.

AU - Sadhur, Z.

AU - Sandhu, A.

AU - Schettino, G.

AU - Schreiber, J.

AU - Shields, W.

AU - Smart, B.

AU - Smith, R.A.

AU - Snijders, A.M.

AU - Spiers, D.

AU - Tantawi, S.

AU - Thomason, J.W.G.

AU - Torrance, Ben

AU - Towe, S.

AU - Underwood, T.

AU - van der Werf, D.P.

AU - Vick, A.

AU - Vikhoreva, A.

AU - Weightman, P.

AU - Welsch, C.P.

AU - Whyte, Colin

AU - Wilson, Robbie

AU - Zakhir, N.

PY - 2026/2

Y1 - 2026/2

N2 - This document, the principal deliverable of the Preliminary Activity, presents the conceptual design for LhARA to serve the ITRF. The conceptual design of the accelerator facility is presented in Chapter 2. Comparison of the laser-hybrid solution with the conventional alternatives has allowed the LhARA approach to be confirmed as the baseline design [15]. The conceptual design for the facility is shown in figure 1.

AB - This document, the principal deliverable of the Preliminary Activity, presents the conceptual design for LhARA to serve the ITRF. The conceptual design of the accelerator facility is presented in Chapter 2. Comparison of the laser-hybrid solution with the conventional alternatives has allowed the LhARA approach to be confirmed as the baseline design [15]. The conceptual design for the facility is shown in figure 1.

KW - radiation therapy

KW - cancer treatment

KW - radiation biology and medicine

KW - pulsed laser

UR - https://epubs.stfc.ac.uk/work/64272701

M3 - Commissioned report

BT - ITRF/LhARA Conceptual Design Report

ER -

ITRF/LhARA Conceptual Design Report

Abstract

Funding

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

The Laser-hybrid Accelerator for Radiobiological Applications

Cockcroft Phase 4

Cite this

ITRF/LhARA Conceptual Design Report

Abstract

Funding

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Projects

The Laser-hybrid Accelerator for Radiobiological Applications

Cockcroft Phase 4

Cite this