Isolation and antibacterial activity of phenylpropanoid derivatives from Ballota nigra

Nicole Didry, Veronique Seidel, Luc Dubreuil, Francois Tillequin, Francois Bailleul

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

In addition to the previously isolated phenylpropanoid glycosides verbascoside 1, forsythoside B 2, arenarioside 3 and ballotetroside 4, another four compounds were isolated from generative aerial parts of Ballota nigra: three phenylpropanoid glycosides, alyssonoside 5, lavandulifolioside 6 and angoroside A 7 and a non-glycosidic derivative (+)-(E)-caffeoyl-l-malic acid 8.The antibacterial activity of the five major compounds (1–4 and 8) was tested against Gram-positive and Gram-negative bacteria. Three of them (1–3) exhibited a moderate antimicrobial activity against Proteus mirabilis and Staphylococcusaureus including one methicillin-resistant strain.
LanguageEnglish
Pages197-202
Number of pages6
JournalJournal of Ethnopharmacology
Volume67
Issue number2
DOIs
Publication statusPublished - 30 Nov 1999

Fingerprint

Ballota
Glycosides
Proteus mirabilis
Methicillin Resistance
Gram-Negative Bacteria

Keywords

  • Ballota nigra
  • antimicrobial activity
  • phenylpropanoid glycosidic esters
  • phenylpropanoid non-glycosidic ester

Cite this

Didry, Nicole ; Seidel, Veronique ; Dubreuil, Luc ; Tillequin, Francois ; Bailleul, Francois. / Isolation and antibacterial activity of phenylpropanoid derivatives from Ballota nigra. In: Journal of Ethnopharmacology. 1999 ; Vol. 67, No. 2. pp. 197-202.
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Isolation and antibacterial activity of phenylpropanoid derivatives from Ballota nigra. / Didry, Nicole; Seidel, Veronique; Dubreuil, Luc; Tillequin, Francois; Bailleul, Francois.

In: Journal of Ethnopharmacology, Vol. 67, No. 2, 30.11.1999, p. 197-202.

Research output: Contribution to journalArticle

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