Abstract
Parasympathetic nerves innervate the detrusor muscle of the urinary bladder, but a non-cholinergic component ofneurotransmission was recognised over 100 years ago (Langley & Anderson, 1895). Subsequently, ATP was identified asthe cotransmitter with acetylcholine (Kasakov & Burnstock, 1983). Here we have determined the effects of P2X receptorantagonists on the non-cholinergic component of neurotransmission.
| Original language | English |
|---|---|
| Pages (from-to) | S200-S200 |
| Journal | Purinergic Signalling |
| Volume | 4 |
| Publication status | Published - May 2008 |
Keywords
- P2 receptors
- P2X1 subtype
- parasympathetic
- cotransmission
- urinary bladder
- acetylcholine