Abstract
Polar fractions of the methanolic extracts of the stem- and root-barks of Schumanniophyton magnificum (Rubiaceae) reduced the effects of cobra venom cardiotoxin in the chick biventer cervicis nerve-muscle preparation in vitro. No activity was observed against a curaremimetic neurotoxin from cobra venom. Further fractionation of the extracts showed that the activity was not due to alkaloidal components, but the active substances could not be identified or isolated.
| Original language | English |
|---|---|
| Pages (from-to) | 273-275 |
| Number of pages | 3 |
| Journal | Planta Medica |
| Volume | 55 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Jan 1989 |
Keywords
- schumanniophyton magnificum extract
- snake venom
- unclassified drug
- animal cell
- biological model
- toxicity