Investigation of the anti-snake venom activity of Schumanniophyton magnificum

P. J. Houghton, A. L. Harvey

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Polar fractions of the methanolic extracts of the stem- and root-barks of Schumanniophyton magnificum (Rubiaceae) reduced the effects of cobra venom cardiotoxin in the chick biventer cervicis nerve-muscle preparation in vitro. No activity was observed against a curaremimetic neurotoxin from cobra venom. Further fractionation of the extracts showed that the activity was not due to alkaloidal components, but the active substances could not be identified or isolated.
Original languageEnglish
Pages (from-to)273-275
Number of pages3
JournalPlanta Medica
Issue number3
Publication statusPublished - 1 Jan 1989


  • schumanniophyton magnificum extract
  • snake venom
  • unclassified drug
  • animal cell
  • biological model
  • toxicity


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