Investigation of the anti-snake venom activity of Schumanniophyton magnificum

P. J. Houghton, A. L. Harvey

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Polar fractions of the methanolic extracts of the stem- and root-barks of Schumanniophyton magnificum (Rubiaceae) reduced the effects of cobra venom cardiotoxin in the chick biventer cervicis nerve-muscle preparation in vitro. No activity was observed against a curaremimetic neurotoxin from cobra venom. Further fractionation of the extracts showed that the activity was not due to alkaloidal components, but the active substances could not be identified or isolated.
Original languageEnglish
Pages (from-to)273-275
Number of pages3
JournalPlanta Medica
Volume55
Issue number3
DOIs
Publication statusPublished - 1 Jan 1989

Keywords

  • schumanniophyton magnificum extract
  • snake venom
  • unclassified drug
  • animal cell
  • biological model
  • toxicity

Fingerprint Dive into the research topics of 'Investigation of the anti-snake venom activity of Schumanniophyton magnificum'. Together they form a unique fingerprint.

  • Cite this