Projects per year
Available treatments for ischaemic stroke are limited despite many years of promising research uncovering many potential therapeutic targets. As a result, stroke ranks as the third most common cause of death and the leading cause of major disability worldwide. Stem cells have shown great success in animal models of stroke and are currently in use in clinical trials to treat stroke patients. However, many issues remain unresolved regarding stem cell therapy including tumourigenicity and graft rejection. Here, we evaluate a novel stem cell, known as small pluripotent stem cells, which are readily available from human blood in large numbers and display typical stem cell characteristics, are not immortilised and as an autograft should circumvent graft rejection.
|Publication status||Published - 27 Jun 2013|
|Event||Uk Preclinical Stroke Symposium: The advantages and pitfalls of using experimental stroke models - University of Leicester, Leicester, United Kingdom|
Duration: 27 Jun 2013 → 27 Jun 2013
|Conference||Uk Preclinical Stroke Symposium|
|Period||27/06/13 → 27/06/13|
- ischaemic stroke
- stem cells
- small pluripotent stem cells
McKittrick, C. M., & Carswell, H. (2013). Investigation of effects of a newly discovered type of blood derived stem cell in a mouse model of stroke. Poster session presented at Uk Preclinical Stroke Symposium, Leicester, United Kingdom.