Projects per year
Abstract
Available treatments for ischaemic stroke are limited despite many years of promising research uncovering many potential therapeutic targets. As a result, stroke ranks as the third most common cause of death and the leading cause of major disability worldwide. Stem cells have shown great success in animal models of stroke and are currently in use in clinical trials to treat stroke patients. However, many issues remain unresolved regarding stem cell therapy including tumourigenicity and graft rejection. Here, we evaluate a novel stem cell, known as small pluripotent stem cells, which are readily available from human blood in large numbers and display typical stem cell characteristics, are not immortilised and as an autograft should circumvent graft rejection.
| Original language | English |
|---|---|
| Publication status | Published - 27 Jun 2013 |
| Event | Uk Preclinical Stroke Symposium: The advantages and pitfalls of using experimental stroke models - University of Leicester, Leicester, United Kingdom Duration: 27 Jun 2013 → 27 Jun 2013 https://www2.le.ac.uk/departments/npb/people/cg95/uk-preclinical-stroke-symposium |
Conference
| Conference | Uk Preclinical Stroke Symposium |
|---|---|
| Country | United Kingdom |
| City | Leicester |
| Period | 27/06/13 → 27/06/13 |
| Internet address |
Keywords
- ischaemic stroke
- stem cells
- small pluripotent stem cells
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Projects
- 1 Finished
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Escalating existing relationships with Thallocell: validation of therapeutic potential of stem cells
McKittrick, C. & Carswell, H.
1/11/12 → 31/12/12
Project: Internally funded project