Abstract
Conference
Conference | Uk Preclinical Stroke Symposium |
---|---|
Country | United Kingdom |
City | Leicester |
Period | 27/06/13 → 27/06/13 |
Internet address |
Fingerprint
Keywords
- ischaemic stroke
- stem cells
- small pluripotent stem cells
Cite this
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Investigation of effects of a newly discovered type of blood derived stem cell in a mouse model of stroke. / McKittrick, Craig Martin; Carswell, Hilary.
2013. Poster session presented at Uk Preclinical Stroke Symposium, Leicester, United Kingdom.Research output: Contribution to conference › Poster
TY - CONF
T1 - Investigation of effects of a newly discovered type of blood derived stem cell in a mouse model of stroke
AU - McKittrick, Craig Martin
AU - Carswell, Hilary
PY - 2013/6/27
Y1 - 2013/6/27
N2 - Available treatments for ischaemic stroke are limited despite many years of promising research uncovering many potential therapeutic targets. As a result, stroke ranks as the third most common cause of death and the leading cause of major disability worldwide. Stem cells have shown great success in animal models of stroke and are currently in use in clinical trials to treat stroke patients. However, many issues remain unresolved regarding stem cell therapy including tumourigenicity and graft rejection. Here, we evaluate a novel stem cell, known as small pluripotent stem cells, which are readily available from human blood in large numbers and display typical stem cell characteristics, are not immortilised and as an autograft should circumvent graft rejection.
AB - Available treatments for ischaemic stroke are limited despite many years of promising research uncovering many potential therapeutic targets. As a result, stroke ranks as the third most common cause of death and the leading cause of major disability worldwide. Stem cells have shown great success in animal models of stroke and are currently in use in clinical trials to treat stroke patients. However, many issues remain unresolved regarding stem cell therapy including tumourigenicity and graft rejection. Here, we evaluate a novel stem cell, known as small pluripotent stem cells, which are readily available from human blood in large numbers and display typical stem cell characteristics, are not immortilised and as an autograft should circumvent graft rejection.
KW - ischaemic stroke
KW - stem cells
KW - small pluripotent stem cells
M3 - Poster
ER -