Projects per year
Abstract
We have investigated the application of narrow-band intracavity spectroscopy for high throughput characterization and detection of reaction products in-situ. An external cavity diode laser (ECDL), wavelength tunable from 810-890 nm, was used to measure varying concentrations of a range of compounds in solution. A linear calibration curve for parts per billion (ppb) concentrations corresponding to 17nM has been recorded. By replacing the grating with a high reflective mirror, parts per trillion (ppt) concentration detection was also achieved corresponding to 340pM. We believe that this technique provides a method for fast and safe measurements of reactions in real time and has potential applications in the pharmaceutical and chemical industry as well as for integrated bio-diagnostics lab-on-a-chip devices.
Original language | English |
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Pages (from-to) | 12-13 |
Number of pages | 1 |
Journal | Chimca Oggi |
Volume | 26 |
Issue number | 1 |
Publication status | Published - 2008 |
Keywords
- intracavity absorption spectrometry
- process analysis
- external cavity diode laser
- pharmaceutical industry
- chemical industry
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Dive into the research topics of 'Intracavity absorption spectrometry: a new technique for process analysis?'. Together they form a unique fingerprint.Projects
- 1 Finished
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Physical and chemical property characterisation in HTT by in-situ analysis and smart data processing
Littlejohn, D. (Principal Investigator), Burns, D. (Co-investigator), Gachagan, A. (Co-investigator), Girkin, J. (Co-investigator) & Hayward, G. (Co-investigator)
EPSRC (Engineering and Physical Sciences Research Council)
1/10/04 → 29/02/08
Project: Research