TY - JOUR
T1 - Interaction between charged lipid vesicles and point- or rod-like trivalent ions
AU - Martin-Molina, Alberto
AU - Lue, Leo
AU - Quesada-Perez, Manuel
AU - Bohinc, Klemen
PY - 2019/6/1
Y1 - 2019/6/1
N2 - This work examines the influence of the charge distribution of trivalent cations on their interaction with soft anionic particles, using a combination of experimental measurements and theoretical modelling. In particular, we perform electrophoresis measurements to determine the zeta-potential of anionic liposomes in the presence of spermidine and lanthanum cations. We work in a range of electrolyte concentration where a reversal in the electrophoretic mobility of the liposomes is expected; however, unlike the case of lanthanum cations, spermidine does not induce mobility reversal of liposomes. As a result, the charge distribution within the counterion appears to be a key factor. This conclusion is supported by a theory that accounts for intra-ionic correlations, which has previously been successfully used to describe the colloidal electric double layer. It allows us to model spermidine as rod-like ions and lanthanum cations as point-like ions in order to test the importance of the ionic geometry in the interactions with soft particles such as lipid vesicles.
AB - This work examines the influence of the charge distribution of trivalent cations on their interaction with soft anionic particles, using a combination of experimental measurements and theoretical modelling. In particular, we perform electrophoresis measurements to determine the zeta-potential of anionic liposomes in the presence of spermidine and lanthanum cations. We work in a range of electrolyte concentration where a reversal in the electrophoretic mobility of the liposomes is expected; however, unlike the case of lanthanum cations, spermidine does not induce mobility reversal of liposomes. As a result, the charge distribution within the counterion appears to be a key factor. This conclusion is supported by a theory that accounts for intra-ionic correlations, which has previously been successfully used to describe the colloidal electric double layer. It allows us to model spermidine as rod-like ions and lanthanum cations as point-like ions in order to test the importance of the ionic geometry in the interactions with soft particles such as lipid vesicles.
KW - rod-like ions
KW - trivalent ions
KW - lipid vesicles
UR - https://www.sciencedirect.com/journal/colloids-and-surfaces-b-biointerfaces
U2 - 10.1016/j.colsurfb.2019.02.010
DO - 10.1016/j.colsurfb.2019.02.010
M3 - Article
VL - 178
SP - 525
EP - 529
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
SN - 0927-7765
ER -