Instrumentation for fluorescence lifetime measurement using photon counting

David J. S. Birch; Graham Hungerford; David McLoskey; Kulwinder Sagoo; Philip Yip

doi:10.1007/4243_2018_2

Instrumentation for fluorescence lifetime measurement using photon counting

David J. S. Birch, Graham Hungerford, David McLoskey, Kulwinder Sagoo, Philip Yip

Research output: Chapter in Book/Report/Conference proceeding › Chapter

61 Downloads (Pure)

Abstract

We describe the evolution of HORIBA Jobin Yvon IBH Ltd, and its time-correlated single-photon counting (TCSPC) products, from university research beginnings through to its present place as a market leader in fluorescence lifetime spectroscopy. The company philosophy is to ensure leading-edge research capabilities continue to be incorporated into instruments in order to meet the needs of the diverse range of customer applications, which span a multitude of scientific and engineering disciplines. We illustrate some of the range of activities of a scientific instrument company in meeting this goal and highlight by way of an exemplar the performance of the versatile DeltaFlex instrument in measuring fluorescence lifetimes. This includes resolving fluorescence lifetimes down to 5 ps, as frequently observed in energy transfer, nanoparticle metrology with sub-nanometre resolution and measuring a fluorescence lifetime in as little as 60 μs for the study of transient species and kinetics.

Original language	English
Title of host publication	Fluorescence in Industry
Editors	Bruno Pedras
Place of Publication	Switzerland
Publisher	Springer
Chapter	3
Pages	103-133
Number of pages	31
Volume	18
ISBN (Electronic)	978-3-030-20033-6
ISBN (Print)	978-3-030-20032-9
DOIs	https://doi.org/10.1007/4243_2018_2
Publication status	Published - 2 Jul 2019

Publication series

Name	Springer Series on Fluorescence
Publisher	Springer
Volume	18

Keywords

DeltaFlex
fluorescence lifetime
HORIBA Jobin Yvon IBH
photon counting
TCSPC

Access to Document

10.1007/4243_2018_2

Birch-etal-2019-Instrumentation-for-fluorescence-lifetime-measurement-using-photon-countingAccepted author manuscript, 1.3 MB

https://link.springer.com/bookseries/4243

2 Finished

UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-106
Birch, D., Chen, Y. & Li, D.
1/10/14 → 30/09/19
Project: Research - Internally Allocated
UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-202
Birch, D., Chen, Y. & Li, D.
1/10/14 → 30/09/19
Project: Research - Internally Allocated

4 Article
1 Chapter (peer-reviewed)
1 Keynote
1 Conference Contribution
More
- 1 Editorial

TCSPC camera for real time video rate FLIM acquisition based on CMOS technology
Hungerford, G., McLoskey, D., Hirsch, R., Yip, P., Birch, D., Johnston, N. & Henderson, R., 7 Feb 2020, In: Biophysical Journal. 118, 3, Supplement 1, p. 308a-308a 1 p.
Research output: Contribution to journal › Conference Contribution › peer-review
12th FluoroFest International Workshop April 24–26, 2017
Birch, D. J. S., 29 Jan 2018, In: Methods and Applications in Fluorescence . 6, 1, 2 p., 020201.
Research output: Contribution to journal › Editorial

Open Access
1 Citation (Scopus)
A lifetime in fluorescence: its measurement and application
Birch, D., 24 Apr 2017.
Research output: Contribution to conference › Keynote

Horiba Lifetime Achievement Award
Birch, David (Recipient), 26 Apr 2017
Prize: Prize (including medals and awards)

Cite this

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title = "Instrumentation for fluorescence lifetime measurement using photon counting",

abstract = "We describe the evolution of HORIBA Jobin Yvon IBH Ltd, and its time-correlated single-photon counting (TCSPC) products, from university research beginnings through to its present place as a market leader in fluorescence lifetime spectroscopy. The company philosophy is to ensure leading-edge research capabilities continue to be incorporated into instruments in order to meet the needs of the diverse range of customer applications, which span a multitude of scientific and engineering disciplines. We illustrate some of the range of activities of a scientific instrument company in meeting this goal and highlight by way of an exemplar the performance of the versatile DeltaFlex instrument in measuring fluorescence lifetimes. This includes resolving fluorescence lifetimes down to 5 ps, as frequently observed in energy transfer, nanoparticle metrology with sub-nanometre resolution and measuring a fluorescence lifetime in as little as 60 μs for the study of transient species and kinetics.",

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doi = "10.1007/4243_2018_2",

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Instrumentation for fluorescence lifetime measurement using photon counting. / Birch, David J. S.; Hungerford, Graham; McLoskey, David; Sagoo, Kulwinder; Yip, Philip.

Fluorescence in Industry. ed. / Bruno Pedras. Vol. 18 Switzerland : Springer, 2019. p. 103-133 (Springer Series on Fluorescence; Vol. 18).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

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AU - Birch, David J. S.

AU - Hungerford, Graham

AU - McLoskey, David

AU - Sagoo, Kulwinder

AU - Yip, Philip

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AB - We describe the evolution of HORIBA Jobin Yvon IBH Ltd, and its time-correlated single-photon counting (TCSPC) products, from university research beginnings through to its present place as a market leader in fluorescence lifetime spectroscopy. The company philosophy is to ensure leading-edge research capabilities continue to be incorporated into instruments in order to meet the needs of the diverse range of customer applications, which span a multitude of scientific and engineering disciplines. We illustrate some of the range of activities of a scientific instrument company in meeting this goal and highlight by way of an exemplar the performance of the versatile DeltaFlex instrument in measuring fluorescence lifetimes. This includes resolving fluorescence lifetimes down to 5 ps, as frequently observed in energy transfer, nanoparticle metrology with sub-nanometre resolution and measuring a fluorescence lifetime in as little as 60 μs for the study of transient species and kinetics.

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KW - photon counting

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Instrumentation for fluorescence lifetime measurement using photon counting

Abstract

Publication series

Keywords

Access to Document

UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-106

UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-202

TCSPC camera for real time video rate FLIM acquisition based on CMOS technology

12th FluoroFest International Workshop April 24–26, 2017

A lifetime in fluorescence: its measurement and application

Horiba Lifetime Achievement Award

Cite this