Projects per year
The current methods of dosage form production do not control the API spatial arrangement especially when using powder blends. This research aims to use Injection Moulding as a novel alternative method taking advantage of the benefits of drug-polymer interactions. Initial studies of paracetamol PVP formulations provided units that contained crystalline paracetamol due to inefficient mixing. Methods to produce solid dispersions prior to injecting such as Hot Melt Extrusions may be necessary.
|Publication status||Published - 5 Sep 2016|
|Event||7th APS International PharmSci Conference - University of Strathclyde, Glasgow, United Kingdom|
Duration: 5 Sep 2016 → 7 Sep 2016
|Conference||7th APS International PharmSci Conference|
|Period||5/09/16 → 7/09/16|
- injection moulding
- dosage forms
- oral drug delivery
- hot metal extrusion
- dissolution profile
Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Mendez Torrecillas, Carlota
1/10/14 → 4/06/19
Project: Research Studentship - Internally Allocated
Wood, S., Halbert, G., & Florence, A. (2016). Injection moulding: a novel approach to the manufacture of homogenous immediate release solid oral dosage forms. Poster session presented at 7th APS International PharmSci Conference, Glasgow, United Kingdom.