Injection moulding: a novel approach to the manufacture of homogenous immediate release solid oral dosage forms

Research output: Contribution to conferencePoster

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Abstract

The current methods of dosage form production do not control the API spatial arrangement especially when using powder blends. This research aims to use Injection Moulding as a novel alternative method taking advantage of the benefits of drug-polymer interactions. Initial studies of paracetamol PVP formulations provided units that contained crystalline paracetamol due to inefficient mixing. Methods to produce solid dispersions prior to injecting such as Hot Melt Extrusions may be necessary.
Original languageEnglish
Publication statusPublished - 5 Sep 2016
Event7th APS International PharmSci Conference - University of Strathclyde, Glasgow, United Kingdom
Duration: 5 Sep 20167 Sep 2016
https://www.ukpharmsci.org/

Conference

Conference7th APS International PharmSci Conference
CountryUnited Kingdom
CityGlasgow
Period5/09/167/09/16
Internet address

Keywords

  • injection moulding
  • dosage forms
  • oral drug delivery
  • hot metal extrusion
  • dissolution profile

Projects

Cite this

Wood, S., Halbert, G., & Florence, A. (2016). Injection moulding: a novel approach to the manufacture of homogenous immediate release solid oral dosage forms. Poster session presented at 7th APS International PharmSci Conference, Glasgow, United Kingdom.