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Abstract
The current methods of dosage form production do not control the API spatial arrangement especially when using powder blends. This research aims to use Injection Moulding as a novel alternative method taking advantage of the benefits of drug-polymer interactions. Initial studies of paracetamol PVP formulations provided units that contained crystalline paracetamol due to inefficient mixing. Methods to produce solid dispersions prior to injecting such as Hot Melt Extrusions may be necessary.
Original language | English |
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Publication status | Published - 5 Sep 2016 |
Event | 7th APS International PharmSci Conference - University of Strathclyde, Glasgow, United Kingdom Duration: 5 Sep 2016 → 7 Sep 2016 https://www.ukpharmsci.org/ |
Conference
Conference | 7th APS International PharmSci Conference |
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Country/Territory | United Kingdom |
City | Glasgow |
Period | 5/09/16 → 7/09/16 |
Internet address |
Keywords
- injection moulding
- dosage forms
- oral drug delivery
- hot metal extrusion
- dissolution profile
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Dive into the research topics of 'Injection moulding: a novel approach to the manufacture of homogenous immediate release solid oral dosage forms'. Together they form a unique fingerprint.Projects
- 1 Finished
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Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Mendez Torrecillas, Carlota
Halbert, G., Robertson, J. & Mendez Torrecillas, C.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/14 → 4/06/19
Project: Research Studentship - Internally Allocated