Cobalt chromium (Co-Cr) alloy metal-on-metal (MOM) hip resurfacing has become increasingly common in younger, more active patients. However, there is growing concern regarding levels of Co-Cr wear debris and ions released. Using the rodent air pouch model, described as a facsimile synovium, we assessed the inflammatory response to artificially generated Co-Cr wear debris.
- hip resurfacing
- cobalt chromium
- rodent air pouch
Akbar, M., Brewer, J. M., & Grant, M. H. (2010). Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model. Toxicology Letters, 196S, S199. https://doi.org/10.1016/j.toxlet.2010.03.675