Increased membrane potentials of human skeletal muscle fibres in explant tissue culture

A. L. Harvey*, J. A. Witkowski

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
Original languageEnglish
Pages (from-to)273-274
Number of pages2
JournalJournal of the Neurological Sciences
Volume44
Issue number2-3
DOIs
Publication statusPublished - 1 Jan 1980

Funding

The average resting potentials of young cultures (up to 2 weeks in vitro) were low, in the region--15 to --30 mV but there was a progressive increase until values of--40 to --80 mV were found in 2-5 week cultures (Table 1). Although it was suspected that higher values were recorded from cultures incubated for 24 hr after arrival in Glasgow, This study was supported by grants from the Muscular Dystrophy Association Inc. (to ALH) and the Muscular Dystrophy Group of Great Britain (to JAW). The authors thank the Medical Research Council for a training award to JGR and the Smith Kline and French Foundation for an equipment grant (to ALH).

Keywords

  • acetylcholine
  • in vitro study
  • maturation
  • methodology
  • muscle
  • muscle fiber membrane potential
  • normal human
  • tissue culture

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