Incidence of hepatitis C virus infection and associated risk factors among Scottish prison inmates: a cohort study

J.K. Champion, A. Taylor, S. Hutchinson, S. Cameron, J. McMenamin, A. Mitchell, D.J. Goldberg

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

To gauge the incidence of hepatitis C virus (HCV) infection and associated risk factors among inmates during their imprisonment, the authors recruited adult males in a long-stay Scottish prison into a cohort study between April 1999 and October 2000. On two occasions (at 0 and 6 months), saliva was collected for anonymous HCV antibody testing and risk behavior data were obtained through a self-administered questionnaire. The participation rate was 85% at both initial recruitment (612/719) and follow-up (375/441; 171 men were ineligible for follow-up). For inmates who reported never having injected drugs, ever having injected drugs, having injected drugs during follow-up, and having shared needles/syringes during follow-up, HCV incidences per 100 person-years of incarceration risk were 1, 12, 19, and 27, respectively. Ever having injected drugs (relative risk = 13.0, 95% confidence interval: 1.5, 114.3) and having shared needles/syringes during follow-up (relative risk = 9.0, 95% confidence interval: 1.1, 71.7) were significantly associated with HCV seroconversion. The effectiveness of existing interventions, including the provision of bleach tablets for sterilizing injection equipment, was suboptimal. The development of methadone maintenance programs in prisons and the creation of drug courts to keep offending drug injectors out of prison might help to reduce transmission in this setting.
Original languageEnglish
Pages (from-to)514-519
Number of pages6
JournalAmerican Journal of Epidemiology
Volume159
Issue number5
DOIs
Publication statusPublished - 2004

Fingerprint

Prisons
Virus Diseases
Hepacivirus
Cohort Studies
Incidence
Pharmaceutical Preparations
Syringes
Needles
Confidence Intervals
Hepatitis C Antibodies
Methadone
Risk-Taking
Saliva
Tablets
Equipment and Supplies
Injections

Keywords

  • hepacivirus
  • substance abuse
  • hepatitis C
  • risk-taking
  • prisons
  • prisoners

Cite this

Champion, J. K., Taylor, A., Hutchinson, S., Cameron, S., McMenamin, J., Mitchell, A., & Goldberg, D. J. (2004). Incidence of hepatitis C virus infection and associated risk factors among Scottish prison inmates: a cohort study. American Journal of Epidemiology, 159(5), 514-519. https://doi.org/10.1093/aje/kwh061
Champion, J.K. ; Taylor, A. ; Hutchinson, S. ; Cameron, S. ; McMenamin, J. ; Mitchell, A. ; Goldberg, D.J. / Incidence of hepatitis C virus infection and associated risk factors among Scottish prison inmates: a cohort study. In: American Journal of Epidemiology. 2004 ; Vol. 159, No. 5. pp. 514-519.
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Champion, JK, Taylor, A, Hutchinson, S, Cameron, S, McMenamin, J, Mitchell, A & Goldberg, DJ 2004, 'Incidence of hepatitis C virus infection and associated risk factors among Scottish prison inmates: a cohort study', American Journal of Epidemiology, vol. 159, no. 5, pp. 514-519. https://doi.org/10.1093/aje/kwh061

Incidence of hepatitis C virus infection and associated risk factors among Scottish prison inmates: a cohort study. / Champion, J.K.; Taylor, A.; Hutchinson, S.; Cameron, S.; McMenamin, J.; Mitchell, A.; Goldberg, D.J.

In: American Journal of Epidemiology, Vol. 159, No. 5, 2004, p. 514-519.

Research output: Contribution to journalArticle

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T1 - Incidence of hepatitis C virus infection and associated risk factors among Scottish prison inmates: a cohort study

AU - Champion, J.K.

AU - Taylor, A.

AU - Hutchinson, S.

AU - Cameron, S.

AU - McMenamin, J.

AU - Mitchell, A.

AU - Goldberg, D.J.

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AB - To gauge the incidence of hepatitis C virus (HCV) infection and associated risk factors among inmates during their imprisonment, the authors recruited adult males in a long-stay Scottish prison into a cohort study between April 1999 and October 2000. On two occasions (at 0 and 6 months), saliva was collected for anonymous HCV antibody testing and risk behavior data were obtained through a self-administered questionnaire. The participation rate was 85% at both initial recruitment (612/719) and follow-up (375/441; 171 men were ineligible for follow-up). For inmates who reported never having injected drugs, ever having injected drugs, having injected drugs during follow-up, and having shared needles/syringes during follow-up, HCV incidences per 100 person-years of incarceration risk were 1, 12, 19, and 27, respectively. Ever having injected drugs (relative risk = 13.0, 95% confidence interval: 1.5, 114.3) and having shared needles/syringes during follow-up (relative risk = 9.0, 95% confidence interval: 1.1, 71.7) were significantly associated with HCV seroconversion. The effectiveness of existing interventions, including the provision of bleach tablets for sterilizing injection equipment, was suboptimal. The development of methadone maintenance programs in prisons and the creation of drug courts to keep offending drug injectors out of prison might help to reduce transmission in this setting.

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