Improving consistency for a Mefenamic acid immediate release formulation

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Abstract

Mefenamic acid (MFA) product performance is highly dependant on particle size and can lead to variable efficacy. In this study, a structured development program was applied, developing a crystalline solid dispersion (CSD) formulation, retaining API properties and improving performance consistency compared to a commercial product.
Original languageEnglish
Number of pages1
Publication statusPublished - 22 Oct 2020
EventCMAC Annual Open Day - Virtual event, Glasgow, United Kingdom
Duration: 21 Oct 202022 Oct 2020

Conference

ConferenceCMAC Annual Open Day
CountryUnited Kingdom
CityGlasgow
Period21/10/2022/10/20

Keywords

  • Mefenamic acid
  • MFA
  • rheology screening
  • hot-melt-extrusion
  • crystalline solid dispersion (CSD)

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